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IOM Panel's Comparative Effectiveness Report Includes Pregnancy Prevention Measures
The U.S. should conduct research to compare the effectiveness of innovative programs aimed at preventing unintended pregnancy, according to a report issued Tuesday by a congressionally convened Institute of Medicine panel, the New York Times reports (Meier, New York Times, 7/1). The recommendations state that these strategies should include "over-the-counter access to oral contraceptives or other hormonal methods, expanding access to long-acting methods for young women, [and] providing free contraceptive methods at public clinics, pharmacies or other locations" (List of Priorities, IOM, 6/26). The report lists 100 health topics that should be prioritized as the Obama administration seeks to increase cost-effectiveness in medicine. The federal stimulus package passed earlier this year allotted $1.1 billion for comparative effectiveness research into different ways of treating certain conditions and addressing various health care issues. According to the Times, the report is a first step in an expansive effort by the administration and health experts to direct medical practice toward scientifically proven treatments, rather than a provider"s personal opinion or a medical product company"s promotional claims. Harold Sox, co-chair of the IOM panel that wrote the report and the editor of the Annals of Internal Medicine, said that based on public comments, the panel decided it was important to include pregnancy prevention and other public health issues in its recommendations (Meier, New York Times, 7/1). The report also recommends that researchers compare different comprehensive care coordination programs, such as the medical home model and chronic disease management, especially in communities known to have health disparities (Simmons, HealthLeaders Media, 6/30).
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Aperio Introduces Industry's First Digital IHC Solution With Integrated Image Analysis For Quantification Of Breast Cancer

Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, is pleased to announce the launch of a digital pathology solution for Immunohistochemistry (IHC) designed specifically for the clinical market. Aperio"s digital IHC solution is the only commercially available FDA-cleared system allowing pathologists to run quantitative IHC image analysis while reading slides on a computer monitor. A digital IHC system significantly streamlines clinical workflow. By using a single system to read digital IHC slides, perform quantitative image analysis, and create professional reports, pathologists can provide faster turn-around times, more informed decision-making, and accurate and consistent test results. Eric F. Glassy, MD, medical director at Pathology Inc., stated, "After switching to Aperio"s digital IHC solution from a different computer-assisted technology, we immediately experienced improved efficiency. More importantly, the interpretation algorithms offer far more control and accuracy, and the reporting capability is superior. We especially appreciate the ability to link thumb nail images on the PDF file to the actual whole slide images. The power and flexibility are simply remarkable." The digital IHC system includes FDA-cleared algorithms for HER2, ER and PR stained breast specimens for diagnosing digital slides for clinical use in pathology. In addition, the system comes with a suite of image analysis algorithms that can be tuned for different tissue types (e.g. breast, colon, prostate), stains (e.g. HER2, ER, PR, Ki-67, P53, EGFR), reagents (e.g. Dako, Ventana) or to correlate algorithm results with other test methods (e.g. FISH, CISH). "An integrated system is key to providing an efficient workflow for pathologists, and a major advantage over add-on image analysis systems," said Dirk Soenksen, CEO of Aperio. "Pathologists can now use Aperio"s sophisticated cell-based image analysis capabilities with the click of a button while reading a slide." Aperio"s versatile digital pathology platform allows laboratories and pathologists to adopt digital pathology in applications like IHC and then expand the utility of the system to many other digital pathology services such as secondary consultations, tumor boards, quality assurance programs, and proficiency testing and training. Aperio


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