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Argenta Discovery And Porsolt Join Forces To Provide Fully-integrated CNS And Pain Contract Drug Discovery Services
Argenta Discovery and Porsolt announced they have entered into an alliance to provide unparalleled CNS and pain drug discovery services and expertise on a fee-for- service basis. The collaboration enables Argenta and Porsolt to undertake fully integrated CNS and pain-focused drug discovery programmes for their clients, from hit identification to development candidate nomination. Both companies bring a wealth of "Big Pharma" industry based experience and know-how in CNS and pain research. This alliance will leverage those key skills for its partners to ensure the rapid generation of high quality development candidates.
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Coma, Vegetative State, Minimally Conscious State: Frequent Misdiagnoses And Inconsistent Standards In Europe Pose Ethical Problems
"Latest research raises important ethical issues concerning our care for patients with chronic consciousness disorders," said Professor Gustave Moonen (Liege, Belgium), past president of the European Neurological Society (ENS), at a press conference at the current ENS Congress. This major meeting in European neurology is gathering more than 2,900 experts from all over the world in Milan. "This is all the more important as studies have shown that more than a third of patients given an initial diagnosis of vegetative state or persistent vegetative state show minimal signs of consciousness under more detailed examination."
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2009 Recipient Of Minority Scholar Award Begins Clinical Research On Leukemia
Alejandro Gutierrez, MD, is the third recipient of the ASH-AMFDP grant, an award designed to help increase the number of underrepresented minority scholars in the field of hematology, and will begin his research into the pathogenesis of T-cell acute lymphoblastic leukemia (T-ALL) this month. The award, the result of a partnership between the American Society of Hematology (ASH) and the Harold Amos Medical Faculty Development Program (AMFDP) of the Robert Wood Johnson Foundation, provides four years of support, including an annual stipend of up to $75,000 and an annual grant of more than $29,000 for research activities.
Cardiovascular

Are Imaging Features Of Hepatic Angiomyolipoma Related To Its Clinical Setting?

This study consisted of 10 patients (three male and seven female) with hepatic angiomyolipoma, with a mean age of 55.1 years (age range, 19-78 years). Of these patients, dynamic contrast CT showed hepatic angiomyolipoma as a hypervascular mass with intratumoral fatty density, absence of a capsule, and prominent central vessels in six sporadic cases, and multiple, small hepatic angiomyolipomas, with or without a fat component in four cases with tuberous sclerosis complex (TSC). Lymphangioleiomyomatosis (LAM) and multiple hepatic angiomyolipomas were found in one patient with TSC. The results suggest that imaging features of hepatic angiomyolipoma are correlated closely with its clinical setting. Sporadic hepatic angiomyolipoma often presents as a solitary large nodule with a varying fat component. In the setting of TSC, hepatic angiomyolipoma often presents as multiple small nodules, with or without fatty tissue, in the peripheral liver. Dynamic CT features of hepatic angiomyolipoma are very characteristic, and correct diagnosis can be made in combination with clinical features. When coexisting intravascular lesions and hepatic angiomyolipomas are found in patients with TSC, LAM should be considered. Reference: Yang B, Chen WH, Li QY, Xiang JJ, Xu RJ. Hepatic angiomyolipoma: Dynamic computed tomography features and clinical correlation. World J Gastroenterol 2009; 15(27): 3417-3420 http://www.wjgnet.com/1007-9327/15/3417.asp Lin Tian World Journal of Gastroenterology


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