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Democrats Are Increasingly Confident About Reform
Despite costs and public skepticism, Democrats are increasingly confident that they"ll enact a vast health care overhaul. McClatchy reports: "The White House is ramping up its behind-the-scenes lobbying of Congress. President Barack Obama is signaling that he could drop some key principles of his campaign if necessary to jump-start negotiations, opening the door to broad tax increases and a plan that could, he now concedes, push people into a government-run insurance program against their will. Senate Democrats also said last week that they were heading toward agreement again after a momentary stall. ... Republicans, too, concede that the Democrats who control Congress and the White House are back on track to push an overhaul into law."
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Inovio Biomedical, National Microbiology Laboratory, And University Of Pennsylvania To Evaluate Candidate DNA Vaccines Against "Swine" Influenza A
Inovio Biomedical Corporation (NYSE Amex: INO), a leader in DNA vaccine design, development and delivery, announced today it has established a new collaboration with the National Microbiology Laboratory of the Public Health Agency of Canada and the University of Pennsylvania to further evaluate Inovio DNA vaccine candidates against swine influenza A (H1N1) virus. As a part of its universal influenza vaccine program, Inovio has designed and manufactured consensus DNA vaccines for H1N1 influenza strains. These consensus vaccines, delivered using Inovio"s proprietary electroporation technology, have the potential to provide protection against a broad scope of existing as well as currently unknown, unmatched influenza strains that could emerge -- one of the perpetual challenges in trying to protect against influenza. The purpose of this collaboration is to test these vaccine candidates against pandemic and seasonal influenza strains in animal models and will include testing against a recently identified swine H1N1 strain.
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The Importance Of Medicaid Continuity For Former Inmates
It is time for states to suspend, rather than terminate, the Medicaid benefits of inmates while they are incarcerated, say correctional health care experts from The Miriam Hospital in a commentary published online by the Journal of General Internal Medicine.
Mental Health

Blood Flow In Alzheimer's Disease

Dr. Jennifer C Palmer and colleagues at the University of Bristol have discovered that endothelin converting enzyme-2 (ECE-2) may cause the decrease in cerebral blood flow seen in Alzheimer"s disease. These results are presented in the July 2009 issue of the American Journal of Pathology. Alzheimer"s disease is the most common form of dementia. Aí² peptide, which accumulates in the brain of Alzheimer"s disease patients, is thought to lead to tightening of the blood vessels and reduction of cerebral blood flood. ECE-2 may contribute to these symptoms by converting an inactive precursor to endothelin-1, which constricts blood vessels. To determine if ECE-2 affects cerebral blood flow in Alzheimer"s disease, Palmer et al examined the expression of ECE-2. They found that ECE-2 levels were elevated in patients with Alzheimer"s disease and that Aí² could increase ECE-2 expression in vitro. These data indicate that ECE-2 levels are increased in response to Aí² and may cause the decrease in cerebral blood flow seen in Alzheimer"s disease. Palmer et al "suggest that [endothelin-1] receptor antagonists, already licensed for treating other diseases, could be of benefit in [Alzheimer"s disease] therapies." Palmer JC, Baig S, Kehoe PG, Love S: Endothelin-Converting Enzyme-2 is Increased in Alzheimer"s Disease. Am J Pathol 2009, 174: 2672-2680 Angela Colmone American Journal of Pathology


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