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Argenta Discovery And Porsolt Join Forces To Provide Fully-integrated CNS And Pain Contract Drug Discovery Services
Argenta Discovery and Porsolt announced they have entered into an alliance to provide unparalleled CNS and pain drug discovery services and expertise on a fee-for- service basis. The collaboration enables Argenta and Porsolt to undertake fully integrated CNS and pain-focused drug discovery programmes for their clients, from hit identification to development candidate nomination. Both companies bring a wealth of "Big Pharma" industry based experience and know-how in CNS and pain research. This alliance will leverage those key skills for its partners to ensure the rapid generation of high quality development candidates.
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Innovative Technology Shatters The Barriers Of Modern Light Microscopy
Researchers at the Helmholtz Zentrum MÃønchen and the Technische Universität MÃønchen are using a combination of light and ultrasound to visualize fluorescent proteins that are seated several centimeters deep into living tissue. In the past, even modern technologies have failed to produce high-resolution fluorescence images from this depth because of the strong scattering of light. In the Nature Photonics journal, the Munich researchers describe how they can reveal genetic expression within live fly larvae and fish by "listening to light". In the future this technology may facilitate the examination of tumors or coronary vessels in humans.
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Health Subcommittee Considers Bill To Eliminate Pre-Emption For Medical Devices
The House Energy and Commerce Health Subcommittee on Tuesday heard testimony on the Medical Device Safety Act of 2009 (HR 1346), which would allow consumers to sue medical device manufacturers in state courts, CQ HealthBeat reports. The bill responds to last year"s Supreme Court ruling that says medical devices with FDA pre-marketing approval can be pre-empted from lawsuits under state law, in accordance with the Medical Device Amendments of 1976. Rep. Frank Pallone (D-N.Y.), who introduced the bill, said that the 2008 Supreme Court ruling "ignor[ed] congressional intent" by providing blanket immunity for medical device makers. According to Rep. John Dingell (D-Mich.), a co-sponsor of the bill, the original 1976 law sought to grant regulatory authority to FDA for medical devices, but it did not aim to eliminate state liability. Committee Chair Rep. Henry Waxman (D-Calif.), another co-sponsor, said last year"s ruling already has caused 1,400 injury cases to be thrown out of court, adding that the threat of litigation provides manufacturers with additional safety incentives. David Vladeck -- a law professor at Georgetown University Law Center who testified at the hearing -- added that immunity from lawsuits "removes incentive to manufacturers to fix devices quickly and get defective devices off the market."Rep. Nathan Deal (R-Ga.) said the class of device that must obtain pre-marketing approval -- which includes pacemakers and replacement heart valves -- represents only 2% of all approved medical devices each year. Rep. Michael Burgess (R-Texas) added that the measure could create an inconsistent system that allows both FDA experts and jurors in various states to make decisions on medical device safety standards. In addition, Rep. Joe Pitts (R-Pa.) cautioned that the bill might encourage manufacturers to limit distribution of their devices to certain states (Kim, CQ HealthBeat, 5/13). Related Editorial
Cardiovascular

CDC Advisory Committee Likely To Place Pregnant Women Near Top Of List For H1N1 Flu Shots

A federal vaccine advisory panel scheduled to meet Wednesday likely will recommend that pregnant women be among the first groups to receive the H1N1 influenza vaccine if a limited number of doses are available, the AP/Atlanta Journal-Constitution reports. The Centers for Disease Control and Prevention usually accepts the recommendations of the panel, called the Advisory Committee on Immunization Practices. According to the AP/Journal-Constitution, health care workers are expected to be the No. 1 priority for receiving the vaccine.For more than 10 years, the panel has recommended that pregnant women get vaccinated for seasonal flu, which can be a threat even to those who are young and healthy. CDC data show that pregnant women, who make up 1% of the U.S. population, have accounted for 6% of H1N1 flu deaths in the country since April, when the pandemic began.British and Swiss health officials have recommended that women consider delaying pregnancies if possible. Most health officials have said that advice oversteps the available evidence, but they have agreed that pregnant women face significant risk from the H1N1 flu. A recent World Health Organization report stated that pregnant women appear to be "at increased risk for severe [H1N1] disease, potentially resulting in spontaneous abortion and/or death, especially during the second and third trimesters of pregnancy." However, WHO has not yet recommended that pregnant women get priority vaccinations. Kevin Ault, an obstetrician at Emory University, said that pregnant women are especially vulnerable because of changes in the lungs and immune system that make it more difficult to overcome respiratory infections (Stobbe, AP/Atlanta Journal-Constitution, 7/28). Reprinted with kind permission from http://www.nationalpartnership.org. You can view the entire Daily Women"s Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women"s Health Policy Report is a free service of the National Partnership for Women & Families, published by The Advisory Board Company. © 2009 The Advisory Board Company. All rights reserved.


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