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Procter & Gamble Pharmaceuticals Launches Asacol(R) HD (Mesalamine) Delayed-Release Tablets For Moderately Active Ulcerative Colitis
Procter & Gamble Pharmaceuticals (P&GP) announced the availability of Asacol HD (mesalamine) delayed-release tablets, which are indicated for the treatment of moderately active ulcerative colitis (UC), a form of inflammatory bowel disease. UC involves inflammation of the lining of the colon and rectum and is typically characterized by flares followed by periods of remission. Moderately active UC is characterized by tougher symptoms than mildly active UC. Asacol HD is proven to help treat these tougher flares of moderately active UC. Asacol HD was approved by the U.S. Food and Drug Administration (FDA) based on evaluations from the ASCEND studies [Assessing the Safety and Clinical Efficacy of a New Dose of 5-ASA (4.8 g/day 800 mg tablet)].
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Second European Country To Commence Cerepro(R) Treatment On Named Patient Basis, England
Ark Therapeutics Group plc (AKT:LSE) announces that Named Patient Supply (NPS) for Cerepro® (sitimagene ceradenovec) has been approved in Finland by the National Agency for Medicines (NAM). The approval follows an application made by a neuro-surgeon in Finland for the use of Cerepro®.
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Individual Bacterial Cells Are Capable Of Quorum Sensing When Confined In Small Volumes
Infections of wounds, pneumonia, etc. in hospitals in particular are often caused by bacteria called Pseudomonas aeruginosa. Once they reach a certain density, colonies of Pseudomonas aeruginosa produce virulence factors and can enter into a slimy state, a biofilm, which prevents antibiotics from penetrating. The process of quorum sensing, which cells use to "sense" cell density, is triggered when the concentration of certain signaling compounds generated by the bacteria reaches a threshold level. A team working with Rustem F. Ismagilov at the University of Chicago has now demonstrated that the absolute number of cells is irrelevant; only the number of bacteria in a given volume plays a role. As the researchers report in the journal Angewandte Chemie, they were even able to trigger quorum-sensing processes in single cells when these were confined in extremely small volumes.
Cardiovascular

CQ Examines House Foreign Affairs Committee Outline To Overhaul U.S. Foreign Aid

Congressional Quarterly examines a "three-page concept paper" issued by the House Foreign Affairs Committee that lays out a plan to overhaul U.S. foreign aid. The committee suggests "giving the administration greater flexibility to control aid in exchange for greater public oversight and a performance- and need-driven allocation system," the news service writes. "The plan would reorganize aid programs around seven purposes, including "reducing poverty and alleviating human suffering," "supporting human rights and democracy," and "expanding prosperity through trade and investment,"" according to CQ. The House committee wants to enhance USAID"s role, "giving the agency a seat on the National Security Council and putting it in charge of the U.S. global AIDS plan and the Millennium Challenge Corporation," the news service writes. Reforming U.S. foreign aid is a "top legislative priority" for Foreign Affairs Committee Chair Rep. Howard Berman (D-Calif.), who earlier this year introduced a bill "to require the administration to put together a development strategy, which he called a "down payment" on greater change," CQ reports. Last week, Senate Foreign Relations Chair John Kerry (D-Mass.) introduced bipartisan legislation "to beef up" USAID, "also intended as a first step toward an overhaul," writes CQ. The story includes reaction to the House committee"s concept paper from Capitol Hill and foriegn aid experts (Graham-Silverman, 8/3). This information was reprinted from globalhealth.kff.org with kind permission from the Henry J. Kaiser Family Foundation. You can view the entire Kaiser Daily Global Health Policy Report, search the archives and sign up for email delivery at globalhealth.kff.org. © Henry J. Kaiser Family Foundation. All rights reserved.


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