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Contrary To Guidelines, Compression Stockings Do Not Reduce The Risk Of Blood Clots After Stroke (CLOTS Study)
Thigh-length graduated support stockings (TL-GCS) do not reduce the risk of blood clots in stroke patients. Since guidelines in the UK and many developed nations recommend use of TL-GCS, such guidelines should now be urgently revised. The findings of the CLOTS trial are published in an Article Online First and in an upcoming edition of The Lancet, written by Professor Martin Dennis, University of Edinburgh, UK, and colleagues. Most of the study"s funding came from the UK Medical Research Council. The findings are to be announced during this week"s European Stroke Conference, Stockholm, Sweden.
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Changing The EU Public Health Dynamic: Better Science, Regulation And Access Policies To Deliver Biopharmaceutical Innovation For Europe's Citizens
Better science, better regulation and better access policies are needed in Europe to support an
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Sticky Protein Helps Reinforce Fragile Muscle Membranes
A new study by scientists at the University of Iowa shows why muscle membranes don"t rupture when healthy people exercise.
Public Health

Can Inflammatory Arthritis Be 'Worse Than Death'?

Patients with inflammatory arthritis completing a health-related quality of life questionnaire report levels of pain that result in their health being rated as "worse than death" by members of the general population. Researchers at the Arthritis Research Campaign Epidemiology Unit at the University of Manchester sought to identify why the health-related quality of life of a significant number of arthritis patients is rated so poorly, and to further investigate the health status of these patients. Arthritis patients report a range of limitations which impair their quality of life including very high levels of pain; this description of extreme pain was the consistent factor in explaining why certain patient"s quality of life was valued as "worse than death". Pain is the symptom of disease that people perceive to have the greatest detriment on quality of life and fear most as a consequence of disease. Rheumatoid arthritis is the most common form of inflammatory arthritis and affects half a million people in the UK. The disease is more common in women than in men. It is a potentially disabling disease with a considerable economic impact. Within ten years of onset of rheumatoid arthritis, at least 50% of patients are unable to hold down a full-time job. "Our findings highlight the burden of disease experienced by patients with arthritis. However quality of life valuations by the general population based on abstract health state descriptions, may not reflect the fact that treatments are available to relieve the pain of arthritis and alter the long-term outcome. We believe that further research is needed to see if the general public would rate this degree of pain differently if they had more information about the character of arthritis" says Dr Mark Harrison PhD of the University of Manchester. This will be discussed in Value in Health, the official journal of the International Society for Pharmacoeconomics and outcomes Research. Value in Health (ISSN 1098-3015) publishes papers, concepts, and ideas that advance the field of pharmacoeconomics and outcomes research and help health care leaders to make decisions that are solidly evidence-based. The journal is published bi-monthly and has a regular readership of over 4,000 clinicians, decision-makers, and researchers worldwide. ISPOR is a nonprofit, international organization that strives to translate pharmacoeconomics and outcomes research into practice to ensure that society allocates scarce health care res wisely, fairly, and efficiently. ISPOR


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