Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles
Burdock Root

St. Jude Medical Completes Implants In U.S. Study Of Deep Brain Stimulation For Parkinson's Disease
St. Jude Medical, Inc. (NYSE:STJ) announced the completion of patient implants in its U.S. pivotal clinical study of deep brain stimulation (DBS) for the symptomatic treatment of Parkinson"s disease, a neurological disorder affecting approximately 6.3 million people worldwide that progressively diminishes a person"s control over his or her movements. The announcement was made at the Movement Disorder Society"s 13th International Congress of Parkinson"s Disease and Movement Disorders in Paris.
generic viagra online
Preventing Toxic Shock Syndrome And Other Severe Diseases
A researcher at The University of Western Ontario has received over $603,000 from the Canadian Institutes of Health Research (CIHR) to investigate how and why a group of bacterial toxins leads to the development of toxic shock syndrome and other serious diseases. John McCormick is an associate professor in the Department of Microbiology and Immunology at the Schulich School of Medicine & Dentistry, and a scientist with the Lawson Health Research Institute. His research is one of 18 projects at Western and Lawson to receive new CIHR operating grants totaling more than $9.55 million.
News of the day
Two New Clinical Studies Show That Limited Exposure To Blood Transfusion Significantly Increases Morbidity And Mortality After Surgery
Masimo (Nasdaq: MASI), the inventor of Pulse CO-Oximetry(TM) and Measure-Through Motion and Low-Perfusion pulse oximetry, announced that two new studies - one conducted in patients undergoing general surgery and published in the Journal of American College of Surgeons and another conducted in patients undergoing cardiac surgery and published in the Anesthesia & Analgesia provide additional new evidence that transfusion of just one or two units of blood significantly increases infection, pneumonia, sepsis, and mortality after surgery.(1,2) These studies suggest that transfusions and their associated risks could be "largely avoided" through implementation of better blood management techniques and "more appropriate indicators" for transfusions.
Cardiovascular

Enzyme Modification Brings 'Corrective Genes' Closer

Scientists from the Universitçİ de Montrçİal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to harmful agents such as chemotherapy, according to a new study published in The Journal of Biological Chemistry. "Our team modified and decoded an enzyme structure," says Joelle Pelletier, a professor at the Universitçİ de Montrçİal"s Department of Chemistry. "We discovered, to our surprise, that our intervention allowed the heart of the enzyme to increase its mobility. This unusual mobility caused the enzyme to resist the chemotherapy agent methotrexate - a result we never predicted and one that offers promise." The research team made its discovery as it sought ways to help correct genetic diseases. "Our goal is to improve the injection of corrective genes in people suffering from genetic diseases," say Pelletier who is also co-director of PROTEO, a Quebec-based research group on the function, structure and engineering of proteins. "This discovery will lead to promising new avenues." "We were intrigued to find the enzyme"s internal flexibility was impacted by our modifications and that this fact played such a crucial role for resistance," says Albert Berghuis, a professor at the McGill University Department of Biochemistry and Canada Research Chair in Structural Biology. "We can now harness this insight to further advance therapies for genetic diseases such as leukemia." Partners in research: This study was funded by the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada. About the study: The paper, "Multiple Conformers in Active Site of Human Dihydrofolate Reductase F31R/Q35E Double Mutant Suggest Structural Basis for Methotrexate Resistance," published in The Journal of Biological Chemistry, was authored by Jordan P. Volpato, Elena Fossati Jonathan Blanchet, Lucie Poulin, Vanessa Guerrero and Joelle N. Pelletier of the Universitçİ de Montrçİal; Brahm J. Yachnin and Albert M. Berghuis of McGill University. Sophie Langlois University of Montreal


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

İ Copyright 2009