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Brazil Proves Developing Countries Can Use Generic Medicines To Fight HIV/AIDS Epidemic
Brazil"s nearly two-decade effort to treat people living with HIV and AIDS shows that developing countries can successfully combat the epidemic. Inexpensive generic medicines are a large part of the solution, say researchers from Brown University and the Harvard School of Public Health.
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Women With Gestational Diabetes During Pregnancy Have A Substantial And Persistently Elevated Risk Of Type 2 Diabetes Post-Birth
Women who develop gestational diabetes (GD) during pregnancy have a seven-and-a-half times increased risk of developing type 2 diabetes post-birth, which lasts throughout their lifetime. However, there is no agreed policy on the long-term follow up of these women and many do not return for the currently recommended 6-week post-birth diabetes check. An Article in this week"s diabetes special issue of The Lancet says that the strength of the association suggests that both disorders have an overlapping cause-and this should act as an incentive for women to attend the recommended post-birth check. This attendance could be an opportunity to provide advice on diet and exercise, and treatments to delay or prevent onset of diabetes-as well as alerting these women to symptoms of future diabetes, and to alert general practitioners responsible for their long-term care.
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New Glucose-regulating Protein Linked With Diabetes Discovered By UCSF
Researchers at the University of California, San Francisco, and collaborators at Harvard Medical School have linked a specialized protein in human muscles to the process that clears glucose out of the bloodstream, shedding light on what goes wrong in type 2 diabetes on a cellular level.
Endocrinology

Fighting Drug-Resistant Flu Viruses

Amid reports that swine flu viruses are developing the ability to shrug off existing antiviral drugs, scientists in Japan are reporting a first-of-its kind discovery that could foster a new genre of antivirals that sidestep resistance problems, according to an article scheduled for the July 23 issue of the ACS" Journal of the Medicinal Chemistry, a bi-weekly publication. Toshinori Sato and colleagues note in the new study that current antiviral drugs, including Tamiflu and Relenza, fight influenza by blocking key proteins that viruses need to reproduce. As the viruses reproduce, however, they can mutate into drug-resistant strains. The researchers describe discovery of a new way to prevent flu viruses from infecting cells in the first place. They identified potential drugs that can block the first step in the infection process, and demonstrated that the substances work in cell cultures. "These results may lead to a new approach in the design of antiviral drugs," they state, noting that it could be used to develop new drugs for a variety of other medical problems. Article: "Inhibition of Influenza Virus Infections by Sialylgalactose-Binding Peptides Selected from a Phage Library" http://pubs.acs.org/stoken/presspac/presspac/full/10.1021/jm801570y Michael Woods American Chemical Society


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