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Advance Toward New Drugs That Turn Genes On And Off
Scientists in Michigan and California are reporting an advance toward development of a new generation of drugs that treat disease by orchestrating how genes in the body produce proteins involved in arthritis, cancer and a range of other disorders. Acting like an "on-off switch," the medications might ratchet up the production of proteins in genes working at abnormally low levels or shut off genes producing an abnormal protein linked to disease. Their report is in the current issue of ACS Chemical Biology, a monthly journal.
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Could Standard Treatment For Traumatic Brain Injury Be Wrong?
Traumatic brain injury not heart disease, stroke or cancer is the number one cause of death and disability in people under 45. Each year, some 1.5 million Americans, including soldiers, athletes, the elderly and children, sustain head injuries, and nearly half of them will be hospitalized and treated in an emergency room or intensive care unit.
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Washington Post Column Examines Issues Surrounding Supreme Court Confirmation Hearings
"When a Supreme Court nominee such as Judge Sonia Sotomayor comes before the Senate for confirmation, she is promised a full, fair hearing," yet "every nominee"s path is booby-trapped by the history of previous confirmation battles," Washington Post columnist David Broder writes. Broder examines prior confirmation hearings, noting that the "[o]ne thing that may make it harder to forget the partisan and ideological battles of the past is that President Obama found reasons to oppose" Chief Justice John Roberts and Justice Samuel Alito while he was in the Senate.During Roberts" confirmation hearing, Obama said that although he was "sorely tempted to vote for Judge Roberts," he had issues with Roberts in cases where "precedent and rules of construction" are insufficient and where justice "can only be determined on the basis of one"s deepest values." Obama added that the rights of women and minorities are dependent on cases in which "the critical ingredient is supplied by what is in the judge"s heart." Obama said Roberts" record on women"s rights and other issues was not strong enough to quell doubts about Roberts" "deepest values."Broder continues, "Based on the Obama precedent, the White House can hardly complain if Republicans push beyond the question of Sotomayor"s qualifications and examine her values -- and her biases." He concludes, "Someday, the Senate may again be satisfied to examine only professional credentials, recognizing the uncertain dynamics of a nine-person bench," but while past precedents survive, "that is not likely" (Broder, Washington Post, 6/4).
Medical Devices

Global AIDS Coordinator Goosby Discusses Slowing Spread Of Disease Among Pregnant Women

Eric Goosby, U.S. global AIDS coordinator and administrator of the President"s Emergency Plan for AIDS Relief, said that slowing the spread of HIV among pregnant women is one of his top priorities, the San Francisco Chronicle reports. In an interview with the Chronicle, Goosby said he also plans to focus U.S. global efforts on education and prevention, as well as convincing other nations to increase their involvement in the fight against HIV/AIDS. Although Goosby stressed the importance of indentifying people who could benefit from antiretroviral drugs, he added that "[w]e"re not going to be able to treat ourselves out of the epidemic, and prevention efforts will need to be continued and increased." He continued, "We also need to look for concentration of patients who have a higher probability of HIV infection, such as pregnant women -- getting them tested, getting them on antiretrovirals, which will prevent transmission to the fetus." Goosby estimated that only around 35% of pregnant women who are HIV positive and could benefit from antiretrovirals receive the drugs.Goosby also praised the efforts of PEPFAR, which was established six years ago under former President George W. Bush. However, he said that more work must be done and that the disease is not controlled. Sub-Saharan Africa, where about 23 million people are living with HIV, "is clearly the epicenter on the planet of this epidemic," Goosby said. He also noted that HIV/AIDS has begun to spread more rapidly among certain populations in Russia, Ukraine, China and Southeast Asia (Doyle, San Francisco Chronicle, 6/24). Reprinted with kind permission from http://www.nationalpartnership.org. You can view the entire Daily Women"s Health Policy Report, search the archives, or sign up for email delivery here. The Daily Women"s Health Policy Report is a free service of the National Partnership for Women & Families, published by The Advisory Board Company. © 2009 The Advisory Board Company. All rights reserved.


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