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For Clues To Fetal Growth Restriction In Cloned Swine, Researchers Look To Imprinted Genes
Researchers at North Carolina State University have found that intrauterine growth restriction (IUGR), which results in low birth weight and long-term deleterious health effects in cloned swine, is linked to a type of gene - known as an imprinted gene - found only in placental mammals. Imprinted genes play an important role in the normal fetal development of all mammals, and this study could have future implications for the study of IUGR in humans.
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DeCODE Discovers A Gene Linked To Risk Of Kidney Stones And Osteoporosis
A discovery by scientists at deCODE genetics (Nasdaq: DCGN) and academic colleagues from Iceland, the Netherlands and Denmark has pointed to a common biological mechanism contributing to both kidney stones and decreased bone mineral density (BMD). About 60% of the population carry two copies of a single-letter variation in the human genome (SNP) on chromosome 21, putting them at roughly 65% greater likelihood of developing kidney stones than those who carry no copies. This single variant may thus account for more than a quarter of the incidence of kidney stones, and in women carriers it is also associated with decreased BMD at the hip and spine.
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RADAR Welcomes Harper's Challenge To End Stigma Surrounding Mental Health Conditions In Parliament, UK
The challenge to the Prime Minister by Mark Harper MP, Shadow Minister for Disabled People, to remove Section 141 of the Mental Health Act which strips an MP of their seat in Parliament if detained under the Act for more than six months, and his tabling of an amendment to the Equality Bill on this issue, are both very welcome and long overdue.
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Hospital Trust Recruiting For Trials Of New Flu Vaccine, UK

Southampton"s university hospitals are to take part in clinical trials of a vaccine that could protect against numerous types of flu - including pandemics such as bird and swine flu. Existing vaccines target only the outside of the flu virus, which frequently changes and varies in different strains of the virus, meaning new vaccines are needed each year. Novel new T-cell vaccines target the internal core of the flu viruses, which do not change very much over time or between strains. The study is being conducted by research staff and clinicians based at the Wellcome Trust Clinical Research Facility (WTCRF) at Southampton General Hospital and the Jenner Institute at Oxford University. "The current approach to tackling flu via the coat of the virus is not adequate because strains are constantly changing, new formulas have to be developed at short notice and then people are only protected for that particular strain," said Dr Saul Faust, director of the WTCRF in Southampton. "If successful, this new type of vaccine that targets the inside of the virus, as opposed to the shell, could potentially offer protection against many different strains of influenza A, including those that cause pandemics." Dr Faust, a specialist in infectious diseases, added: "Such an advanced vaccine would be suitable for all ages at any time of year and, as the substance of the vaccination would not change from year to year, there would be no need for annual injections." Three hundred healthy volunteers aged between 18 and 45 are required to take part. Initially, volunteers will have a blood test to see if they are immune to a particular strain of flu and 26 people who do not have this immunity will then go ahead to trial the new vaccine in the second part of the study. Southampton University Hospitals NHS Trust


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