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Washington Post Examines Focus On Abortions Later In Pregnancy After Tiller Murder
The Washington Post on Friday examined the renewed attention on abortion procedures performed later in pregnancy following Kansas provider George Tiller"s shooting death on Sunday. Tiller was one of the few physicians in the U.S. who performed late abortions. The Post reports that these abortions make up a small portion of the 1.2 million abortions performed each year -- more than 88% of abortions are performed in the first trimester and less than 1% are performed after 21 weeks" gestation. Data published in 2001 from 15 states and New York City show that as many as 2,400 abortions after 24 weeks" gestation were performed in the U.S. that year, according to Stanley Henshaw, a senior fellow at the Guttmacher Institute. He added that most of those abortions likely were performed in the 25th or 26th week.Henshaw said that little is known about the circumstances surrounding third trimester abortion procedures and that "information just isn"t available." The government does not collect detailed data regarding the number of such procedures, who is performing them and under what circumstances. In addition, abortion providers who perform the procedure later in pregnancy supply very little published information, the Post reports. According to the Post, most abortion providers will not perform the procedure after 22 or 24 weeks" gestation because of legal and other concerns, social stigma, or inadequate training and lack of experience. A 2001 survey of 1,819 abortion providers indicated that 18 clinics and 12 hospitals performed abortions at 26 weeks" gestation. However, the Post reports that the number of providers offering abortions later in pregnancy likely has declined in correlation with the decreasing number of overall providers. Henshaw said the number of providers offering the procedure later in pregnancy also likely has declined.Abortion-rights supporters say that third-trimester abortions are performed only when medically necessary, such as when a fatal abnormality is detected in the fetus or a life-threatening complication in the woman is discovered. Other circumstances include cases when the woman suffers serious emotional issues or is undergoing cancer treatment, the Post reports. Vicki Saporta, president of the National Abortion Federation, said that women who experience such pregnancies have "no good choice" and "nee[d] to terminate their pregnancies to protect their own health." Tiller "provided both the emotional and physical care for women in that situation," she said (Stein, Washington Post, 6/5).Los Angeles Times Profiles Abortion Provider Hern The Los Angeles Times on Friday profiled Warren Hern, a Colorado-based abortion provider who performs the procedure later in pregnancy and was a close friend of Tiller"s. Hern has provided abortions since 1973 when the Supreme Court legalized the procedure with Roe v. Wade. He said he "felt doing abortions was the most important thing I could do with my life." Hern opened the Boulder Abortion Clinic in 1975, and in the 1980s authored and self-published a textbook, Abortion Practice. He said that he eventually began to focus on abortion procedures later in pregnancy, which currently make up the majority of his practice. Such abortions usually are performed because of medical complications in the woman or abnormalities in the fetus. Patients at Hern"s clinic receive counseling to explain the procedure and to ensure the woman wants it, although he said many women have already made their decision with their own physician. Hern said that although Tiller"s death has been an emotional situation, his clinic is "pretty busy taking care of people who said they couldn"t find anyone else" to perform abortions later in pregnancy (Correll, Los Angeles Times, 6/5).Bond Set for Tiller Shooting Suspect Sedgwick County, Kan., District Judge Warren Wilbert on Thursday set a $5 million bond for Scott Roeder, the man charged with shooting and killing Tiller, the AP/Yahoo! News reports. A preliminary hearing for Roeder is scheduled for June 16. If convicted, Roeder face
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New Snapshots Show States Vary Widely In Providing Quality Health Care, USA
The Agency for Healthcare Research and Quality"s annual release of state-by-state quality data continues to give states mixed reviews for the quality of care they provide. As in previous years, AHRQ"s 2008 State Snapshots show that no state does well or poorly on all quality measures.
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Lawmakers Address Nurse And Primary Care Physician Shortages
A pending House bill would aim to address the nursing shortage by allowing "20,000 additional nurses to enter the U.S. each year for the next three years as a temporary measure to fill the gap," Business Week reports. The bill was introduced by Representative Robert Wexler, D-Fla., in May. If it doesn"t "pass on its own, lawmakers may include it in a comprehensive immigration reform package." Hospital administrators in some areas that face nursing shortages support the bill as "temporary relief," but "Wexler"s bill is opposed by labor unions, whose leaders say it would undermine efforts to produce a steady domestic workforce while sapping other nations" nurses. [President Barack] Obama has also expressed skepticism about the idea that the U.S. needs to import nurses, in particular because the U.S. unemployment rate continues to rise." Instead, Obama has said, the focus should be on improving the res to fund education for new American-born nurses. "The $787 billion economic stimulus bill included $500 million to address shortages of health workers in the U.S., with about $100 million to promote nursing and increase capacity at U.S. nurse-training schools."
Medical Devices

Lorus Announces Publication Of A Novel Analytical Method Confirming The Pharmacological Action Of Its Anticancer Drug LOR-2040

Lorus Therapeutics Inc. (TSX:LOR)("Lorus"), a biopharmaceutical company specializing in the research and development of pharmaceutical products and technologies for the management of cancer, today announced a publication from investigators at the Ohio State University (OSU). The article entitled "A LC-MS/MS Method for the Analysis of Intracellular Nucleoside Triphosphate Levels" was published in the peer-reviewed journal, Pharmaceutical Research in the June issue (Vol. 26(6):1504-15). In the article data was presented from studies using a novel analytical method. The results confirm pharmacological activity of LOR-2040, in five leukemia cell lines and in bone marrow samples of a patient with acute myeloid leukemia (AML) treated with LOR-2040 in a Phase II clinical trial. A significant decrease in intracellular deoxynucleoside triphosphate levels required for DNA synthesis in tumor cells treated with LOR-2040 confirmed the target inhibition effect of LOR-2040. These studies were conducted by a clinical research team involved in the clinical trial of LOR-2040 and high dose cytarabine for treatment of refractory and relapsed AML, under the overall direction of Dr. Guido Marcucci and Dr. Kenneth Chan at the OSU Comprehensive Cancer Center. "This method developed and validated by the OSU investigators has paved a novel way to monitor activity of LOR-2040 and could serve as a valuable tool to allow us to design improved treatment strategies," said Dr. Aiping Young, Lorus" President and CEO. "Continued collaboration with the OSU investigators is fostering unprecedented levels of understanding as to how LOR-2040 works and how this drug should be most effectively targeted to benefit cancer patients." About LOR-2040 LOR-2040 is an RNA-targeted drug that specifically targets the R2 component of ribonucleotide reductase, which is required for DNA synthesis and cell proliferation. Through downregulation of R2, LOR-2040 has demonstrated strong antitumor and antimetastatic activity in a variety of tumor types in both in vitro and in vivo models and is under study in a multiple Phase I/II clinical program, including an advanced Phase II clinical trial with LOR-2040 and high dose Ara-C (HiDAC) in refractory and relapsed Acute Myeloid Leukemia (AML). The R2 target has been described as a malignant determinant that is elevated in a wide range of tumor types, which can cooperate with a variety of cellular cancer causing genes known as oncogenes to enhance tumor growth and metastatic potential. Lorus Therapeutics Inc.


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