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Determining Success Or Failure In Cholesterol-Controlling Drugs
Researchers at the University of California, San Diego have discovered that a complex network of interactions between drugs and the proteins with which they bind can explain adverse drug effects. Their findings suggest that adverse drug effects might be minimized by using single or multiple drug therapies in order to fine-tune multiple off-target interactions.
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British Public Putting Their Eyesight At Risk
- Nearly two thirds (59%) of the British public are neglecting
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Brain Activation Can Predict The Strategies People Use To Make Risky Decisions
Watching people"s brains in real time as they handle a set of decision-making problems can reveal how different each person"s strategy can be, according to neuroscientists at the Duke University Medical Center.
Nutrition

Marijuana Damages DNA And May Cause Cancer

Using a highly sensitive new test, scientists in Europe are reporting "convincing evidence" that marijuana smoke damages the genetic material DNA in ways that could increase the risk of cancer. Their study can be found in the June 15 issue of ACS" Chemical Research in Toxicology, a monthly journal. Rajinder Singh and colleagues note that toxic substances in tobacco smoke can damage DNA and increase the risk of lung and other cancers. However, there has been uncertainty over whether marijuana smoke has the same effect. Scientists are especially concerned about the toxicity of acetaldehyde, present in both tobacco and marijuana. However, it has been difficult to measure DNA damage from acetaldehyde with conventional tests. The scientists describe development and use of a modified mass spectrometry method that showed clear indications that marijuana smoke damages DNA. "In conclusion, these results provide evidence for the DNA damaging potential of cannabis [marijuana] smoke, implying that the consumption of cannabis cigarettes may be detrimental to human health with the possibility to initiate cancer development," the article states. "The data obtained from this study suggesting the DNA damaging potential of cannabis smoke highlight the need for stringent regulation of the consumption of cannabis cigarettes, thus limiting the development of adverse health effects such as cancer." Journal: Chemical Research in Toxicology "Evaluation of the DNA Damaging Potential of Cannabis Cigarette Smoke by the Determination of Acetaldehyde Derived N2-Ethyl-2÷´-deoxyguanosine Adducts" FULL TEXT ARTICLE. CONTACT: Rajinder Singh, Ph.D. University of Leicester Leicester, U.K. Michael Woods American Chemical Society


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