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Enzyme Modification Brings 'Corrective Genes' Closer
Scientists from the Universitçİ de Montrçİal and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to harmful agents such as chemotherapy, according to a new study published in The Journal of Biological Chemistry.
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Studies Examine Morning Sickness Drug, Progesterone Use To Prevent Premature Birth
The following summarizes news coverage on two pregnancy-related studies. ~ Morning sickness: The commonly prescribed heartburn drug metoclopramide -- sold generically and under the brand-names Reglan, Octamide and Maxolon -- can be used to treat morning sickness without harming the health of the fetus, according to a study published on Thursday in the New England Journal of Medicine, Time reports. The drug, which also has anti-nausea properties, is not FDA-approved for use in pregnant women in the U.S., though it is commonly prescribed in European and other countries to treat morning sickness (Park, Time, 6/10). According to the Los Angeles Times, U.S. physicians occasionally prescribe metoclopramide to treat severe morning sickness cases. The new study found that there were no statistically significant differences between infants born to women who took metoclopramide and those who did not. Researchers said that the findings "provide reassurance regarding the safety of metoclopramide for the fetus when the drug is given to women to relieve nausea and vomiting during pregnancy." The study involved 81,703 births among women enrolled in Israel"s largest health HMO, including 33,458 who used the drug (Maugh, Los Angeles Times, 6/11). Jennifer Niebyl, a professor of obstetrics and gynecology at the University of Iowa, said, "There are very few drugs approved for use in the first trimester of pregnancy. But this study could lead to metoclopramide getting approved to treat morning sickness because this is good data with big numbers" (Time, 6/10).~ Progesterone: The hormone progesterone was not effective at preventing premature births among women pregnant with twins, despite evidence suggesting its effectiveness at preventing premature births in single pregnancies, according to a University of Edinburgh study published in the journal Lancet, Reuters reports. Multiple pregnancies have a larger health risk for women and significantly increase the likelihood of miscarriage, premature birth and long-term health problems. The study involved 500 women who took either progesterone or a placebo daily for 10 weeks. Although previous studies have shown that progesterone might prevent premature birth in certain high-risk pregnancies, the new findings show the treatment did not reduce the likelihood of premature delivery or a fetus dying in utero in twin pregnancies. Twenty-five percent of women delivered or had a fetus die before 34 weeks in the progesterone group, compared with 20% in the placebo group (Kahn, Reuters, 6/10).
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Fountain Of Youth? Cutting Calories May Add Years To Your Life
Growing scientific evidence indicates that people who adhere to a special calorie-restricted diet can improve their health and could potentially add years to their lifespan, according to an article in the current issue of Chemical & Engineering News, ACS" weekly newsmagazine.
Medical Devices

Policy Win For Independent Health Workforce And Training, Australia

The Royal Australian College of General Practitioners (RACGP) welcomes the amendments made to the Health Workforce Australia Bill 2009 this week. The Bill establishes the Health Workforce Authority (HWA) as proposed by the Council of Australian Governments (CoAG). The legislation was passed subject to an amendment, which restricts the HWA from having responsibility for the accreditation of clinical education and training, which includes general practice vocational training. "This is a significant win for our patients and a strong endorsement of the independent accreditation of general practice education and training by the Australian Medical Council; a longstanding process, which has always been supported by the RACGP," said Dr Chris Mitchell, RACGP President and GP in northern New South Wales. "The RACGP believes in the general practice profession setting and accrediting its education standards. We believe in an accreditation system that ensures the best outcomes for our patients; in our submissions to the CoAG process we have argued that this is best delivered by a system that ensures the accreditation of specialist medical education and training remains independent of governments. "We welcome the recognition in the Bill that the RACGP and other specialist medical colleges are, as accredited by the Australian Medical Council, the appropriate bodies to set the standards for training." The RACGP continues to advocate for similar amendments to CoAG"s Health Practitioner Regulation National Law (Bill B) and will be providing feedback on the exposure draft over the coming weeks. Members can read the full set of RACGP submissions to the CoAG consultation process at http://www.racgp.org.au/reports. The Royal Australian College of General Practitioners (RACGP)


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