Categories
Cardiovascular
Diagnostics
Endocrinology
Health Insurance
Medical Devices
Mental Health
Nutrition
Oncology
Public Health
Sexual Health
Popular Articles
Burdock Root

Valeant Pharmaceuticals Reports Encouraging Final Results With Taribavirin Phase IIb Study
Valeant Pharmaceuticals International (NYSE: VRX) reported final results for its Phase IIb dose-finding clinical trial for taribavirin, a prodrug of ribavirin which is in development for the treatment of chronic hepatitis C in conjunction with a pegylated interferon. The study in treatment naive genotype 1 infected subjects was of standard design, consisting of 48 weeks of treatment with a 24-week follow-up period. It explored three weight-based doses of taribavirin: 20 mg/kg, 25 mg/kg and 30 mg/kg vs. ribavirin 800-1400 mg/day. Throughout the 72-week trial, all doses of taribavirin demonstrated comparable efficacy (sustained virologic response (SVR)) to ribavirin with consistently lower levels of anemia. In addition, relapse rates in the 25 mg/kg and 30 mg/kg arms were comparable with the ribavirin arm; supporting the premise that higher dose weight-based taribavirin may be as effective as weight based ribavirin. Valeant plans to present the full final data at the American Association for the Study of Liver Disease (AASLD) later this year.
generic viagra online
The Lancet Calls For Improvements To Epilepsy Services, UK
Policy makers must increase investment in services to improve the lives of people with epilepsy, according to The Lancet Neurology this month.
News of the day
APEX Guides: Helping PBC Leaders To Become World Class Commissioners
The first three guides - Clinical Engagement, Governance and Prioritising Investment - will be launched at the Practice Based Commissioning National Forum, on 1 July. A fourth guide, on Patient and Public Engagement, will be published over the summer and a fifth, on Procurement, is already in the pipeline and expected to be published in September.
Health Insurance

Weight Loss Effective In Preventing Falls For The Obese

In addition to greatly improving overall health and longevity, losing weight is an effective fall prevention strategy for persons with obesity, according to a new study from the American College of Sports Medicine. A study by Michael Madigan, Ph.D., found that obese persons who lost even less than 10 percent of their body weight (about 25 pounds for a 300-pound person) or more significantly improved their balance. Madigan and his study team used a fall test where subjects were held in a leaning-forward position, released, and then challenged to recover their balance. Computer simulations were then used to determine how much weight loss improved balance. When subjects lost around 8.5 percent of their body weight, they were able to regain balance from a starting lean position one degree larger than before weight loss. "Studies have shown that obese persons fall nearly twice as much as non-obese individuals," Madigan said. "Falls have also been reported as the most common cause of injury for the obese. Losing even just a small amount of weight can improve balance and potentially reduce this risk." And, Madigan says, so can strength training - although more strength training than weight loss is needed to improve balance. Computer simulations also showed subjects who increased their strength by around 15 percent experienced a similar level of improved balance as the 8.5-percent weight loss group. "How an obese person chooses to improve their balance, whether through weight loss or increased strength training, is a personal choice," Madigan said. "Ideally, those with obesity would strive to do both, in addition to an aerobic fitness program, to stave off numerous diseases and other negative obesity side effects in addition to improving balance." American College of Sports Medicine


Add your comment:
Name:
Site address: http://
Your message:
Enter today\\\\'s date, 2 digits
(spam protection):

© Copyright 2009