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Primary Care Gets Boost From Stimulus Money, Experiment On 'Medical Home'
"Secretary of Health and Human Services Kathleen Sebelius announced Tuesday that $200 million will be available for grants, loans, loan repayments and scholarships for the training of some 8,000 health professionals by the end of fiscal 2010," Congressional Quarterly reports. The money will "provide targeted investments in primary care, nursing, faculty development, and equipment purchases that will shore up the workforce as we prepare for reform," HHS Secretary Kathleen Sebelius said" (7/28).
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TRP Ion Channel Drug Can Treat Allergy-Induced Asthma In Mouse Study
Hydra Biosciences, Inc., a biotech company developing novel ion channel drugs, has announced that research published by Hydra Biosciences scientists and collaborators at Yale University for the first time identified the ion channel TRPA1 as playing an essential role in allergic asthma and demonstrated that Hydra"s TRPA1 antagonist HC-030031 effectively treated allergic asthma in mice. The paper, titled "A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma," will appear this week in Proceedings of the National Academy of Sciences (PNAS).
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Developing Gene Therapy To Fight Blindness
An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being funded in part by a $1.5 million grant from the Prince Salman Center for Disability Research in Saudi Arabia, where the recessive gene mutation that leads to the eye disease RP has been found in children from several families.
Mental Health

Withdrawal Of Co-proxamol Linked To Reduction In Suicides And Accidental Poisonings, UK

Withdrawal of the painkiller co-proxamol from the UK market has led to a major reduction in suicides and accidental poisonings involving the drug, without an increase in deaths from other painkillers, finds research published on bmj.com today. Co-proxamol was the most commonly prescribed drug used in suicides and was responsible for 766 deaths between 1997 and 1999 in England and Wales. Concerns about large numbers of fatal poisonings led the Committee on Safety in Medicines to announce in 2005 the phasing out of co-proxamol from use in the UK by the end of 2007. Whether this initiative has been effective and reduced poisoning deaths has not been assessed. So Keith Hawton from the University of Oxford and colleagues used national records to compare the impact of the announcement of co-proxamol withdrawal on prescribing practices and deaths from co-proxamol with other painkillers mostly likely to be used instead of co-proxamol (cocodamol, codeine, codydramol, dihydrocodeine, non-steroid anti-inflammatory drugs) in England and Wales between 1998 and 2007. Findings showed a steep fall (59%), in the prescribing of co-proxamol following the announcement in 2005, accompanied by significant increases in the prescribing of other painkillers including cocodamol (up by more than 20%), paracetamol (up by more than 13%), and codeine (up by more than 8%). These changes in prescribing practices were accompanied by a 62% reduction in, or 295 fewer suicides, and 349 fewer deaths when accidental poisonings were included, without an increase in deaths involving other painkillers and prescribed drugs. This, say the authors, shows that concerns about the possible substitution of suicide method involving other painkillers were unfounded. These findings suggest that the UK initiative has been an effective measure and highlights how regulatory authorities "can have an important public health function, as has been found for measures restricting pack sizes of analgesics sold over the counter," they conclude. British Medical Journal


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