Cardiovascular
In a disappointing move, the Food and Drug Administration (FDA) did an about face in issuing a final regulation classifying dental amalgam without calling for stringent precautions for pregnant women and children. Last June, a court settlement filed by the Consumers for Dental Choice required the FDA to withdraw claims of mercury amalgam"s safety from its Web site and issue an advisory indicating: "Dental amalgams contain mercury, which may have neurotoxic effects on the nervous systems of developing children and fetuses."
What
Some HIV/AIDS advocates have voiced disappointment with the level of HIV/AIDS funding in President Obama"s proposed $63 billion, six-year global health initiative, VOA News reports. According to VOA News, the advocates say that Obama has not met pledges he made as a presidential candidate, while other say that the "picture is more complicated." According to the Global AIDS Alliance, Obama previously pledged to dedicate $50 billion over five years to HIV/AIDS, TB and malaria, but has instead proposed $51 billion over six years. GAA Executive Director Paul Zeitz said this proposal translates into significantly less annual funding for PEPFAR (Kilner, VOA News, 5/19). Zeitz said, "President Obama has a moral obligation to demonstrate global leadership on behalf of the poorest and most marginalized people of the world, especially in Africa," adding, "But by turning his back on those needs, the president is betraying the trust of tens of millions of people" (Pflanz, Daily Telegraph, 5/18). Advocates estimate that the funding shortfall could result in about one million people going without HIV/AIDS treatment and about 2.9 million women going without treatment to prevent mother-to-child HIV transmission. James Kamau, coordinator for the Kenya Treatment Action Movement, said that one effect of Obama"s proposal is that other donor countries could take similar actions, leading to additional cuts. "In Kenya here we say when the lead sheep limps then it does not get the others to the pastures," Kamau said, adding, "Now if [Obama] cuts back funding on the Global Fund, then the rest of the people will follow suit" (VOA News, 5/19). Some have welcomed Obama"s proposal, saying that it has expanded the focus of global health initiatives to include other health issues that can be treated at a low cost but have not received as much attention, VOA News reports. Obama"s proposal includes $12 billion for these additional areas of focus, including more emphasis on maternal health and health infrastructure, according to VOA News.According to VOA News, Obama"s proposal might be more than Congress is willing to allocate during the economic crisis. The current budget resolution under consideration by Congress would allocate $51 billion for foreign aid in FY 2010, almost $3 billion less than what Obama requested (VOA News, 5/18). African Government Spending on Health
A bill (HR 252) introduced this month in the Ohio House would require a pregnant woman seeking an abortion to obtain written consent from the fetus" biological father, the Cincinnati Enquirer reports. If the woman does not know the identity of the biological father, she would have to provide proof of paternity tests of potential fathers. The bill is sponsored by Rep. John Adams (R) and co-sponsored by four other Republicans.The bill would establish "abortion fraud" as a first-degree misdemeanor, punishable by up to six months in jail and a fine of up to $1,000. Repeat offenders could be charged with a fifth-degree felony, punishable by up to one year in jail and up to a $2,500 fine. The bill is not clear as to who could be fined or jailed. Becki Brenner, president of Planned Parenthood of Southwest Ohio, said that she believes doctors would be the ones ultimately fined or jailed.Brenner criticized the bill, saying that a woman would have to pay at least $1,400 for each DNA test if she is unsure who the father is. Brenner called the legislation "a burden on a woman," adding that the whole purpose behind the bill is to make it harder to obtain a legal abortion. She said, "Hopefully, [the bill] won"t even get debate in the committee" because it is "blatantly anti-woman."Paula Westwood, executive director of Right to Life of Greater Cincinnati, said that her group supports the bill. She added, "I would think men would want to have these rights."According to the Enquirer, the bill does not have the support of the House Democratic majority. The current version of the bill has not been assigned to a committee, and it is unlikely to pass the House, much like past bills seeking new restrictions on abortion (Craig/Preston, Cincinnati Enquirer, 7/24).
Lawmakers are considering two new taxes to help pay for a health care overhaul: a tax on fatty foods and taxing insurers on so-called Cadillac plans. Both proposals were scrutinized in news articles.
The U.S., WHO and representatives from 13 African countries on Monday launched an effort to boost the standards for quality medical labs on the continent, VOA News reports. At the start of a three-day meeting of policy makers in Kigali, Rwanda, African health officials signed off an accreditation system for laboratories across the continent. "Better medical labs mean better patient care - and officials say the only way to ensure a laboratory is a good one is to have it accredited," the news service writes (De Capua, 7/27).
Uganda"s Health Ministry announced Monday it has ordered investigations into whether the deaths of 17 patients living with HIV in Northern Uganda were caused by their inability to get antiretroviral (ARV) drugs, the AP/mlive.com reports. According to Zainab Akol, manager of the ministry"s HIV/AIDS control program, the ministry is exploring "whether apart from the lack of ARVs, another disease like malaria or any epidemic could have contributed to the deaths," according to the news service.
Walter and Eliza Hall Institute scientists have created a weakened strain of the malaria parasite that will be used as a live vaccine against the disease. The vaccine, developed in collaboration with researchers from the US, Japan and Canada, will be trialled in humans from early next year.
The Healthcare Association of New York State (HANYS) called on the State Legislature to pass much-needed legislation that will better protect the rights of incapacitated patients and spare family members from the nightmare of helplessly watching their loved one"s health care wishes go unfulfilled.
Maternal exposure to nanoparticles of titanium dioxide (TiO2) affects the expression of genes related to the central nervous system in developing mice. Researchers writing in BioMed Central"s open access journal Particle and Fibre Toxicology found that mice whose mothers were injected with the nanoparticles while pregnant showed alteration in gene expression related to neurological dysfunction.
E-mail, search engines, smart phones and other new technologies that can disseminate new medical information quickly led to an almost immediate change in clinical practice for drug-eluting stents, according to a study reported in Circulation: Cardiovascular Quality and Outcomes.
The HealthGrades Fourth Annual Bariatric Surgery Trends in American Hospitals Study released today identifies 88 hospitals as "best" performers (five-star rated), with mortality rates, complication rates and patient lengths of stay that are dramatically lower than poorly rated hospitals.
By a wide margin, health care leaders believe that individuals should have a choice of public and private health plans, and strongly support other central components of health reform such as innovative provider payment reform and a national insurance health exchange with strong standard-setting authority. In addition, two-thirds (68%) of opinion leaders feel it is urgent to enact comprehensive health care reform this year, according to the latest Commonwealth Fund/Modern Healthcare Health Care Opinion Leaders Survey.
Georgia has received $63.9 million in Ryan White Program grants to fund treatment and other services for people living with HIV, the Atlanta Journal-Constitution reports. Grant recipients include county health departments and community organizations. The funding will be used to provide outpatient health services, health insurance coverage and support services, such as transportation and housing. According to the Journal-Constitution, more than $1.79 billion in Ryan White funding was allocated nationwide. Several HIV/AIDS organizations said that the funding is necessary to continue providing services for people living with the disease. Tracy Elliot, executive director of AID Atlanta, said that the funding is "critical," noting that more than 18,000 HIV/AIDS cases have been reported in Georgia. He continued, "We would have a lot of deaths without [the funding]. There would be significantly more illnesses without it and significantly more transmission of the disease without it." According to Elliot, "[m]edical treatment and medications are of no value if people cannot have access to them" (Poole, Atlanta Journal-Constitution, 5/19).
Using both animal and human cells, Duke University Medical Center scientists have demonstrated that a single lung cell can become one of two very different types of airway cells, which could lead to a better understanding of lung diseases.
Researchers at The University of Queensland have helped identify genes that could hold the key to treating a common and deadly type of breast cancer.
The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial testing a drug treatment for pulmonary hypertension in adults with sickle cell disease nearly one year early due to safety concerns. In an interim review of safety data from 33 participants who completed 16 weeks of treatment, researchers found that, compared to participants on placebo (dummy pill), participants taking sildenafil (Revatio) were significantly more likely to have serious medical problems. The most common problem was episodes of severe pain called sickle cell crises, which resulted in hospitalization. No deaths have been associated with the drug in the clinical trial.
Scientists from the Universitē© de Montrē©al and McGill University have re-engineered a human enzyme, a protein that accelerates chemical reactions within the human body, to become highly resistant to harmful agents such as chemotherapy, according to a new study published in The Journal of Biological Chemistry.
Elron Electronic Industries Ltd. (NASDAQ & TASE: ELRN) announced, that further to it previous announcement on July 28, 2009, Medingo Ltd., a group company held 92% by Elron and its subsidiary, RDC - Rafael Development Corporation Ltd., has received formal clearance from the Food and Drug Administration ("FDA"), to market its Solo™ MicroPump Insulin Delivery System in the United States.
A groundbreaking study in Cancer Prevention Research, a journal of the American Association for Cancer Research, suggests that having the human papillomavirus (HPV) improves survival in squamous cell carcinoma of the head and neck. Furthermore, African Americans had far less HPV infection than whites, which led to worse survival.
Trusted health care s and continuity of care may help reduce the risk of prostate cancer deaths in African-American men, according to a study published in the current issue of the journal Cancer. James Mohler, MD, Chair of the Department of Urology at Roswell Park Cancer Institute (RPCI), and William R. Carpenter, PhD, Department of Health Policy and Management at the University of North Carolina, are lead investigators.
A federal vaccine advisory panel scheduled to meet Wednesday likely will recommend that pregnant women be among the first groups to receive the H1N1 influenza vaccine if a limited number of doses are available, the AP/Atlanta Journal-Constitution reports. The Centers for Disease Control and Prevention usually accepts the recommendations of the panel, called the Advisory Committee on Immunization Practices. According to the AP/Journal-Constitution, health care workers are expected to be the No. 1 priority for receiving the vaccine.For more than 10 years, the panel has recommended that pregnant women get vaccinated for seasonal flu, which can be a threat even to those who are young and healthy. CDC data show that pregnant women, who make up 1% of the U.S. population, have accounted for 6% of H1N1 flu deaths in the country since April, when the pandemic began.British and Swiss health officials have recommended that women consider delaying pregnancies if possible. Most health officials have said that advice oversteps the available evidence, but they have agreed that pregnant women face significant risk from the H1N1 flu. A recent World Health Organization report stated that pregnant women appear to be "at increased risk for severe [H1N1] disease, potentially resulting in spontaneous abortion and/or death, especially during the second and third trimesters of pregnancy." However, WHO has not yet recommended that pregnant women get priority vaccinations. Kevin Ault, an obstetrician at Emory University, said that pregnant women are especially vulnerable because of changes in the lungs and immune system that make it more difficult to overcome respiratory infections (Stobbe, AP/Atlanta Journal-Constitution, 7/28).
On Tuesday, President Obama pitched Democrats" health reform plans to senior citizens and assured them that Medicare benefits would not be cut to pay for covering the uninsured, the New York Times reports. Meanwhile, members of Congress said they were "deluged" with constituent calls expressing concern over the future of their Medicare coverage.
"Secretary of Health and Human Services Kathleen Sebelius announced Tuesday that $200 million will be available for grants, loans, loan repayments and scholarships for the training of some 8,000 health professionals by the end of fiscal 2010," Congressional Quarterly reports. The money will "provide targeted investments in primary care, nursing, faculty development, and equipment purchases that will shore up the workforce as we prepare for reform," HHS Secretary Kathleen Sebelius said" (7/28).
Senator John Kerry (D-Mass.), chairman of the Senate Foreign Relations Committee, and ranking member, Senator Richard Lugar (R-Ind.), on Tuesday "introduced a bill to overhaul the U.S. system for providing global development aid," the Boston Globe reports (Smith, 7/29). The legislation was also introduced by Senators Robert Menendez (D-NJ) and Bob Corker (R-Tenn.), according to a release from Menendez"s office (7/28).
The Senate Appropriations Labor, HHS, Education and Related Agencies Subcommittee on Tuesday approved by voice vote its fiscal year 2010 spending bill draft, which excludes funding for abstinence-only sex education programs and, unlike the House bill, does not include language lifting the ban on the use of federal funding for needle exchange programs, CQ Today reports. According to the article, Committee Chair Tom Harkin (D-Iowa) "confirmed that the bill will not contain funding for abstinence-only education programs when the full committee marks it up on Thursday. Instead, the draft will contain funding for more comprehensive sex education, which can include teaching abstinence." Harkin also said that the Senate bill does not contain language lifting the ban on the needle exchange funding because that is "a matter for conference" (Wolfe, 7/28).
In what will be the Stem Cell Awareness Association"s seventh awareness rally, past patients, interested physicians, and prospective patients will meet in Manchester to learn about stem cell technologies and discuss the various current treatments available throughout the world.
Recycling is a critical component in the process of transmitting information from one neuron to the next, and a large protein called Tweek plays a critical role, said an international consortium of researchers led by Baylor College of Medicine in a report in the current issue of the journal Neuron.
In response to the publication of Demonstrating Quality: The Sixth National Adult Cardiac Surgical Database Report (1) which examined outcomes for adult cardiac patients British Heart Foundation (BHF) Associate Medical Director Dr Mike Knapton said:
The latest findings of the North Carolina-Louisiana Prostate Cancer Project reveal potential new targets for reducing racial disparities in prostate cancer survival and highlight the importance of the health care delivery system. The study reports differences in physician trust, access to care, and continuity of care between African American and Caucasian men which result in advanced prostate cancer at the time of diagnosis and contribute to the higher death rate among African American men. The study is published in the early view issue of Cancer online July 27, 2009.
Helicobacter pylori, nonsteroidal anti-inflammatory drug use and smoking are the most important risk factors for peptic ulcer. Alcohol intake may also play a role in the development of gastric ulcers. Psychological stress may also have an impact on the onset and course of ulcer disease. However, very little is known as to whether childhood adversities involving financial problems, conflicts in the family, problems with alcohol, and matters of personal security are associated with peptic ulcer.
An international team of scientists and clinicians from the United States and Saudi Arabia are working to develop gene therapy for treating a rare, hereditary retinal disease. The therapy has been shown to restore lost vision in animal models of retinitis pigmentosa (RP). Their work is being funded in part by a $1.5 million grant from the Prince Salman Center for Disability Research in Saudi Arabia, where the recessive gene mutation that leads to the eye disease RP has been found in children from several families.
The Juvenile Diabetes Research Foundation, a leader in setting the agenda for diabetes research worldwide and the largest charitable funder and advocate of type 1 research, has announced that it has launched an on-line service for people with type 1 diabetes and their families to easily find information about clinical trials for drugs, treatments, and therapeutics for diabetes and its complications.
This study consisted of 10 patients (three male and seven female) with hepatic angiomyolipoma, with a mean age of 55.1 years (age range, 19-78 years). Of these patients, dynamic contrast CT showed hepatic angiomyolipoma as a hypervascular mass with intratumoral fatty density, absence of a capsule, and prominent central vessels in six sporadic cases, and multiple, small hepatic angiomyolipomas, with or without a fat component in four cases with tuberous sclerosis complex (TSC). Lymphangioleiomyomatosis (LAM) and multiple hepatic angiomyolipomas were found in one patient with TSC.
Registration is underway for the 10th International Conference on Systems Biology (ICSB). The conference will be held at Stanford University from August 30th - September 4th.
Memory is a fundamental function of nerve cells in the brain, and loss of memory is a key symptom in many people with Alzheimer"s disease.
The Committee for a Responsible Federal Budget urges policymakers to make controlling health care cost growth the focus of health care reform (see Principle #1: Slowing Health Care Cost Growth ).
Schering-Plough Corporation (NYSE: SGP) announced that the U.S. Food and Drug Administration (FDA) Psychopharmacologic Drugs Advisory Committee voted unanimously in favor of SAPHRIS(R) (asenapine) sublingual tablets as effective and safe for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults and in favor of use in acute treatment of schizophrenia in adults. If approved by FDA, SAPHRIS would be the first psychotropic drug to be approved initially for both of these indications.
Doing something unusual, like knocking on wood or patting yourself on the head, while taking a daily dose of medicine may be an effective strategy to help seniors remember whether they"ve already taken their daily medications, suggests new research from Washington University in St. Louis.
While the massive weight loss associated with gastric bypass surgery is beneficial, some patients may face malnutrition, poor wound healing and infection as their immune systems adjust to the extreme decrease in food consumption, according to a Michigan State University researcher.
A researcher at The University of Western Ontario has received over $603,000 from the Canadian Institutes of Health Research (CIHR) to investigate how and why a group of bacterial toxins leads to the development of toxic shock syndrome and other serious diseases. John McCormick is an associate professor in the Department of Microbiology and Immunology at the Schulich School of Medicine & Dentistry, and a scientist with the Lawson Health Research Institute. His research is one of 18 projects at Western and Lawson to receive new CIHR operating grants totaling more than $9.55 million.
Oregon Health & Science University has been named a Circle of Life Award winner for its innovative program that improves the care of patients near the end of life or with life-threatening conditions.
House Democrats on Wednesday made a deal with fiscally conservative Blue Dog Democrats on a health reform bill that "would reduce the overall cost of the package and ensure more funding for rural hospitals, concessions that could allow the Energy and Commerce Committee to finish its consideration of the legislation," The Washington Post reports. The deal will be considered on the House floor no earlier than September, according to several lawmakers. House lawmakers plan to conclude their markup of the legislation in the Energy Committee Thursday.
President Barack Obama on Wednesday took his health reform pitch on the road again, with stops in Raleigh, N.C., and Bristol, Va., where he appealed to Americans who already have health insurance.
"The healthcare overhaul fight in Washington is bursting into America"s living rooms, and interests from many bands on the political spectrum are trying to transform an often wonky debate over 1,000-page bills into an emotional pitch that can be captured in 30 seconds," The Boston Globe reports.
Under economic pressure, states are slashing funding for health services from Connecticut to California. The cuts frustrate providers and lawmakers are looking for ways to limit harm.
This week long observation of the importance of breastfeeding is organized by the World Breastfeeding Week organization (worldbreastfeedingweek.org). The theme this year is the importance of breastfeeding during emergency situations. It is important that when natural or man-made disasters strike that all involved remember the importance of maintaining and supporting breastfeeding of infants affected by the disaster.
Video Game Teaches Kenyan Teens HIV Prevention
It takes a spleen to mend a broken heart - that"s the conclusion of a surprising new report from researchers at the Massachusetts General Hospital (MGH) Center for Systems Biology, directed by Ralph Weissleder, MD, PhD. In the July 31 issue of Science the team reports how, in following up an intriguing observation, they discovered an unexpected reservoir of the immune cells called monocytes in the spleen and went on to show that these cells are essential to recovery of cardiac tissue in an animal heart attack model.
Scientists from Scotland and Singapore have unraveled a mystery that has perplexed scientists since red wine was first discovered to have health benefits: how does resveratrol control inflammation? New research published in the August 2009 print issue of The FASEB Journal, not only explains resveratrol"s one-two punch on inflammation, but also show how it - or a derivative - can be used to treat potentially deadly inflammatory disease, such as appendicitis, peritonitis, and systemic sepsis.
Views are being sought on European proposals for a revised regime for regulating the placing on the market and use of biocides.
The American Medical Student Association (AMSA), the nation"s oldest and largest, independent association for physicians-in-training, is pleased to present the graduates of the AMSA Foundation-VITAS End of Life Education Fellowship Program. Five medical students have spent the past six weeks immersing themselves in end of life (EOL) care issues.
In response to the publication of the report, Lynda Hamlyn, Chief Executive of NHS Blood and Transplant, said:
HHS Secretary Kathleen Sebelius and Agriculture Secretary Tom Vilsack announced today that prevention and partnership will guide their departments" efforts to safeguard the food Americans eat every day. Both Secretaries announced new strategies that focus on prevention and depend on working closely with growers, food processors and consumers to achieve their goals.
A new chemical imaging technique could one day help in the fight against atherosclerosis, suggests research published in the August 2009 edition of the Journal of the Royal Society Interface.
Recent questions about the death of Michael Jackson have focused media attention on the commonly used intravenous anesthetic propofol. In the April 2009 issue of Anesthesia & Analgesia, the leading clinical journal for anesthesiologists, Robert R. Kirby, James M. Colaw and Michael M. Douglas reported on a 24-year-old woman whose 2005 death was attributed to propofol toxicity.
Pfizer Inc (NYSE: PFE) and Medivation, Inc. (NASDAQ: MDVN) announced the initiation of a Phase 3 trial of the investigational drug dimebon (latrepirdine) in patients with Huntington disease. The international safety and efficacy trial, known as HORIZON, is designed to evaluate the potential benefits of dimebon on cognition (thinking and memory) in patients with Huntington disease. The companies also announced that the U.S. Food and Drug Administration (FDA) has granted orphan drug designation to dimebon for the treatment of Huntington disease.
The advantages of volunteering reported by adults aged 55 and older are largely dependent upon the characteristics of the activities in which they participate, according to a recent article appearing in The Gerontologist (Vol. 49, No. 1). The lead author is Nancy Morrow-Howell, PhD, of Washington University in St. Louis.
Intrauterine devices "seem like the perfect form of contraception: simple to use, long-lasting, reversible, hormone-free, economical," Slate columnist Kate Klonick writes. She asks, "So why are American women so late to this party? Perhaps the better question is: Why did they leave the party to begin with?"Klonick explains the benefits of IUDs, calling them a "foolproof method of birth control" and noting that they are 99% effective and "can last up to 10 years." Although IUDs can cost between $300 and $500, it is a one-time expense that is often covered by insurance, according to Klonick. She notes that although efficacy studies show that birth control pills, patches and vaginal rings can be "99% effective in a clinical setting, real-life compliancy -- like forgetting to take the pill at the same time every day -- reduces its success rate." Klonick adds that the availability of hormone-free IUDs makes them an "ideal" option for "women prone to some of the negative effects of hormonal birth control, like weight gain, mood swings, acne or high blood pressure."According to Klonick, IUDs were used by almost 10% of U.S. women taking birth control in the late 1970s but are now used by less than 2% of such women. She writes that Katharine O"Connell, a gynecologist at Columbia University who specializes in contraception, believes IUDs still carry a stigma "due to the erroneous belief that they"re highly dangerous" partly due to a number of deaths that occurred in the early 1970s tied to a specific brand of IUD known as the Dalkon Shield. Because of bad publicity surrounding the devices, "the U.S. pharmaceutical industry abandoned the research and manufacturing of IUDs in the mid-1980s, claiming the devices were no longer profitable," Klonick states. According to O"Connell, most experts now agree that the Dalkon Shield"s problems were related to its design, which made users more susceptible to infection, and a lack of testing for sexually transmitted infections before insertion.There are now two major brands of IUDs -- Mirena and ParaGard -- on the U.S. market, but physican training remains a problem, according to Klonick. She writes that studies show that premedical students are not educated regarding IUDs to the extent they are about oral contraceptive pills. O"Connell also noted that many medical schools limit classes on contraception to one lecture, which often omits IUDs. Klonick writes, "This lack of training can leave many doctors feeling uncomfortable recommending the once-controversial devices to their patients." She adds that many physicians who know how to insert and remove IUDs "still refuse to recommend it to childless patients because of the device"s checkered history." She concludes, "With Mirena advertising on television, the downturn in the economy forcing people to economize, and more women concerned about the long-term effects hormones have on their bodies, perhaps the IUD"s stigma will finally become a thing of the past" (Klonick, Slate, 7/29).
Lobbying efforts by Doctors Hospital at Renaissance, in Edinburg, Texas, have steered hundreds of thousands of dollars to key lawmakers in hopes of blocking reforms that would restrict ownership of hospitals by physicians, the Associated Press/Dallas Morning News reports in a follow up to an article in yesterday"s New York Times. Doctor-owned hospitals "have been blamed for helping drive up health care costs." The hospital in question was "featured in a June article by The New Yorker that singled the area out for some of the highest health care costs in the country." The article has become a talking point for the White House on reform (7/30).
International patients spending $3 billion a year on care in the United States are helping fund a gap for hospitals waiting with bated breath to see how health care reform will affect them, Marketplace reports.
"While Americans may complain about the high cost of health care, they"re still willing to shell out roughly $34 billion a year out-of-pocket on alternative therapies that aren"t covered by insurance, a new study shows," USA Today reports. Spending on the complementary and alternative therapies has increased by 25 percent in the last decade, according to the study by the Centers for Disease Control and Prevention and the National Institutes of Health (Szabo, 7/30).
"A U.S. plan to rely on swine flu vaccines without ingredients to stretch the supply [known as adjuvants] would reduce the number of available shots just when other countries need them most, the British journal Lancet said in an editorial," Bloomberg writes. On July 7, the WHO recommended the use of adjuvants - "mixes of oil and water that trigger a stronger response in the body to antigen, the substance that induces immunity" - to increase the global vaccine supply. Though adjuvants are not approved for flu vaccines in the U.S., HHS" decision to declare the H1N1 flu a public health emergency in April gave the FDA the go-ahead to use "unapproved medical products including adjuvants," according to Bloomberg.
San Francisco area HIV/AIDS organizations are urging lawmakers to restore millions of dollars in funding for HIV/AIDS prevention and treatment programs that were cut from the California budget by Gov. Arnold Schwarzenegger (R) this week, KCBS.com reports. "The governor has removed a substantial amount of our capacity to make sure that people know their HIV status," Dana Van Gorder of Project Inform said, adding "Services that are keeping people who are already HIV positive healthy will be reduced with a major impact on their health." A rally is planned to take place next week at the state building in San Francisco to protest the cuts, according to the article (7/30). David Brinkman of the Desert AIDS Project in Palm Springs, "says the budget cuts are literally a matter of life and death," KESQ.com reports. The Desert AIDS Project is hoping that planned fundraising will temporarily offset the cuts to services in the Palm Springs area (Diaz, 7/30).
Researchers at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health are working with Argentina"s National Institute of Infectious Diseases, the National Administration of Laboratories and Health Institutes (ANLIS), and Roche 454 Life Sciences to decode the complete genomic sequences of influenza pandemic (H1N1) 2009 virus from patients with severe respiratory disease. The scientists will be comparing sequences of viruses associated with the current outbreak in Argentina with those found in other locations to determine if there are differences that may be linked to higher mortality rates or provide insights into virus evolution.
Low blood pressure is also known as hypotension. For millions of people who suffer from hypertension (high blood pressure) hypotension may seem great. If symptoms are mild hypotension usually requires no treatment. However, it can cause serious heart disorders, fainting and also lead to neurological and endocrine disorders. If hypotension is severe key organs can become deprived of oxygen and nutrients and the body can go into shock, a life-threatening condition.
Data presented today at the 8th European Congress on Menopause
Scientists who found a new human immunodeficiency virus (HIV) in a Cameroonian woman living in Paris, have discovered it is an unusual
"American seniors have a lot at stake in this health care reform debate and
Response Genetics Inc. (Nasdaq: RGDX), a company focused on the development and sale of molecular diagnostic tests for cancer, will announce the results of separate analyses of KRAS gene mutations and TS and RRM1 gene expression in non-small cell lung cancer (NSCLC) during the 13th World Conference on Lung Cancer, which will be held July 31 to August 4. Results will provide insights into which patient subtypes are most likely to benefit from the commonly prescribed chemotherapies pemetrexed and gemcitabine.
Sinovac Biotech Ltd. (NYSE AMEX: SVA), a leading provider of vaccines in China, announced today that the clinical trial of its A/H1N1 influenza vaccine is proceeding well. All of the volunteers have received their first shot of the vaccine and, during the three-day observation of safety, the preliminary tests on the A/H1N1 influenza vaccine have indicated that the vaccine is safe and reliable in humans.
New sequencing and analysis of six strains of Chlamydia will result in improved diagnosis of the sexually transmitted infection. This study provides remarkable insights into a new strain of Chlamydia that was identified in Sweden in 2006 after spreading rapidly across the country by evading most established diagnostic tests.
UroToday.com - Pelvic floor muscle exercise (PFME) is most appropriate for patients with mild-to-moderate stress urinary incontinence (SUI). To obtain therapeutic efficacy, it is crucial that PFME be performed correctly and consistently. Without appropriate training; however, up to 30% of patients are not aware of how to perform PFME.
A former Clinton administration official said last week that there aren"t enough doctors in America to handle the increase in patients if health reform covers more uninsured, NPR reports.
To mark the International Day Against Homophobia (IDAHO) on 17 May, a lesbian, gay, bisexual and transgender (LGBT) youth group in Telford and Shropshire is calling for local people to be aware that "Being gay is only part of who you are". The group chose this slogan to put across the message that LGBT people should not be defined by their sexuality alone, but by who they are as individuals. The I-mix group, run by HIV and sexual health charity Terrence Higgins Trust (THT), will be distributing posters and flyers across the region to encourage LGBT young people interested in joining to get in touch.
California"s experience with insurance exchanges could prove a valuable lesson for the nation"s flirtation with such pools for covering large numbers of people, The Wall Street Journal reports.
A new deal to balance California"s budget may have serious repercussions for the health of the state"s children, while South Carolina grapples with health cuts of its own. Meanwhile, New Jersey may become one of the first states to publically disclose hospital errors.
Unhealthy Compromise The Baltimore Sun
A recently passed House spending bill that lifts the ban on the use of federal funding for needle exchange programs, which included an amendment addressing the locations of needle exchanges, "according to many health and human rights advocates, has been diluted to the point that it won"t help the same urban areas most afflicted by" blood-borne illnesses such as HIV, the Washington Independent reports. House Appropriations Committee Chair David Obey (D-Wis.) added an amendment to the bill that prohibits needle exchanges from operating "within 1,000 feet of schools, daycare centers and other areas where children are likely to congregate," according to the Independent. Obey "included the restriction, not because he supports it, but to appease conservative critics who might have killed the entire provision otherwise," the article states. William McColl, political director for AIDS Action, said, "In an urban environment, that really is a restriction on almost anywhere."
UNICEF Executive Director Ann Veneman, who visited Nigeria to launch the country"s first ever National Child Health Week, said an unacceptably high number of children in the country are dying from preventable diseases, and she called on Nigerian government officials to provide integrated healthcare, Xinhua reports (8/3).
With the "last resort" antibiotic Vancomycin now plagued by the first signs of bacterial resistance, a scientific collaboration centered at Duke University has identified how a candidate successor antibiotic known as Ramoplanin A2 can kill pathogenic bacteria by interrupting how they form their cell membranes.
Assisted dying laws do not mean that fewer people use palliative care, according to a study published on bmj.com today.
Regular yoga practice is associated with mindful eating, and people who eat mindfully are less likely to be obese, according to a study led by researchers at Fred Hutchinson Cancer Research Center.
A new diagnostic tool developed by Van Andel Research Institute (VARI) scientists has shown promising results when used with patients of pancreatic cancer, one of the deadliest forms of cancer due to the difficulty of diagnosing it in its early stages. The method, which studies carbohydrate structures in the bloodstream, could lead to the development of blood tests that can detect cancer more effectively.
Whether it"s highlighted in major news headlines about Argentinean affairs and Ponzi schemes, or in personal battles with obesity and drug addiction, individuals regularly succumb to greed, lust and self-destructive behaviors. New research from the Kellogg School of Management examines why this is the case, and demonstrates that individuals believe they have more restraint than they actually possess - ultimately leading to poor decision-making.
Responding to the Innovation, Universities, Science and Skills Committee (IUSS) report on "Students and Universities" Professor Paul Wellings, Chair of the 1994 Group of leading research intensive universities and Vice-Chancellor of Lancaster University said:
Children"s after-school activities often consist of sedentary behavior such as watching television, but after-school programs that offer physical activity and healthy snacks could be the best place for children"s health.
The new anti-wrinkle facial filler Dysport, which could be used as an alternative to Botox, noticeably reduced frown lines between the eyes, according to users and independent reviewers in a study involving plastic surgeons at UT Southwestern Medical Center.
Boehringer Ingelheim announced today at the International Association for the Study of Lung Cancer"s 13th World Conference on Lung Cancer (WCLC), San Francisco, CA, the initiation of a Phase III clinical study of BIBW 2992 as first-line treatment in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. BIBW 2992 (planned brand name Tovok™) is the first orally-administered, irreversible dual inhibitor of EGFR and HER2,1 to reach Phase III development in NSCLC.2
Speaker Nancy Pelosi issued the following statement tonight on the vote by the House Energy and Commerce Committee to pass the America"s Affordable Health Choices Act, the third House committee to pass the bill this month. The House Ways and Means Committee and Education and Labor Committee approved the bill earlier this month:
A new Equality and Diversity Council that will strengthen the national focus on improving quality in the National Health Service, was announced by the Department of Health today.
Sirtuin proteins have been shown to promote longevity in many organisms, and increased expression of one sirtuin protein, SIRT3, has been linked to increased human lifespan. New data, generated in mice, by Mahesh Gupta and colleagues, at the University of Chicago, Chicago, has revealed that Sirt3 helps protect the mouse heart.
Moffitt Cancer Center and Frantz BioMarkers, LLC have signed a license agreement on phospholipid biomarkers of ovarian cancer. Frantz BioMarkers, which has been granted exclusive worldwide rights to Moffitt"s interests in the biomarkers, will pay initiation, developmental milestone and license maintenance fees, and royalties on sales. Moffitt and Frantz BioMarkers will collaborate on ovarian cancer biomarker research, combining use of these licensed markers with lipid markers developed independently by Frantz BioMarkers.
The recent H1N1 pandemic has highlighted the importance of identifying public health measures which can help to mitigate flu virus transmission. Researchers conducted a prospective cluster-randomized trial to test whether improved hand hygiene or surgical face masks could reduce the spread of flu within households.
A new study, published in the journal Menopause, found postmenopausal women with vasomotor symptoms-which include hot flashes and night sweats-had lower bone mineral density in the spine and hip.
Heart specialists at St. Joseph Hospital in Orange, Calif. have performed a new procedure in which they repaired a hole in the patient"s heart through a tiny incision, offering the patient a much safer alternative verses open heart surgery.
Of the 600,000-800,000 people trafficked across international borders each year, 50 percent are under 17. It is estimated that by 2010, human trafficking will be the No. 1 crime worldwide.
PEAK Surgical, Inc. announced the launch of the PEAK((R)) PlasmaBlade TnA (Tonsil and Adenoid) tissue dissection device following 510(k) clearance from the U.S. Food and Drug Administration (FDA). This new product is indicated for cutting and coagulation of soft tissue during otolaryngology (ear, nose and throat [ENT]) surgery, including removal of the tonsils and adenoids.
An article published Online First exposes the facts of the poisoning of Ukrainian President Victor Yushchenko in 2004. It is the work of Professor Jean Saurat, from the Swiss Centre for Human Applied Toxicology, and the University Hospital, in Geneva, Switzerland, and his collaborators. It establishes that there is a need for routine analytical techniques to test for metabolites of TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) which is a type of dioxin and the poison that was used. This will help to provide proper treatment.
Cervical cancer, or cancer of the cervix, is cancer of the entrance to the uterus (womb). The cervix is the narrow part of the lower uterus, often referred to as the neck of the womb. Cervical cancer occurs most commonly in women over the age of 30.
A compound initially isolated from a soft coral (Capnella imbricata) collected at Green Island off Taiwan, could lead scientists to develop a new set of treatments for neuropathic pain - chronic pain that sometimes follows damage to the nervous system. Currently this form of pain is very poorly controlled by the usual analgesics (aspirin like drugs (NSAIDS) or even opioids like morphine) and novel treatments are urgently required. The conclusion of a paper published in the British Journal of Pharmacology is that this new compound could be a candidate.
While most people who commit violent acts against abortion providers are "characterized as lone nuts," they actually are often associated with "extremist" antiabortion-rights groups, Ms. editor Michele Kort writes in the magazine"s Summer 2009 issue. These groups "track the whereabouts" of providers and "deliver white-hot rhetoric that paints someone like" murdered abortion provider George Tiller "as a murderer rather than a healer," Kort says. Extremists within the antiabortion-rights movement have "even promoted the assassinations of abortion providers as "justifiable homicides,"" leaving the ""lone nuts" ... as good as licensed to kill," she adds. According to Kort, one in five abortion clinics is the target of repeat violence annually. Since the early 1990s, nine doctors and clinic workers have died as a result of violent attacks, Kort states.Tiller, who was shot to death on May 31 in the foyer of his Wichita, Kan., church, "also faced a concerted attack" in Kansas courts, Kort continues. The legal efforts against Tiller included two grand jury investigations resulting from citizen petition drives led by Operation Rescue and other antiabortion-rights groups. Kort notes that neither jury found any basis for indictment against Tiller. In addition, former Kansas Attorney General Phill Kline in 2004 subpoenaed Tiller"s patient records, which Kort writes was "supposedly to determine if he hadn"t reported statutory rapes of pregnant girls under 16." The court dismissed the criminal charges Kline filed in the case. Paul Morrison, the current Kansas attorney general, in 2006 "surprisingly" charged Tiller with 19 misdemeanors for failing to get a second opinion on some abortion procedures, Kort states. She also comments, "After nearly two years of legal proceedings, the jurors in the case delivered a resounding "not guilty" in just 25 minutes."The legal issues were "exhaustive and expensive" for Tiller, according to Kort. She adds that Dan Monnat, Tiller"s attorney in Wichita, said that Tiller ""held up like a soldier"" during the legal battles. Kort reports that Tiller"s friends "worried about him" nonetheless. Susan Hill -- who operates several abortion clinics and referred patients needing the procedure later in pregnancy to Tiller -- said he once told her that he would not retire because "I can"t leave these women. There"s no one else for them."Kort also profiled Miriam Kleiman, a woman who had an abortion at Tiller"s clinic after her fetus was diagnosed with a severe brain malformation at 28 weeks" gestation (Kort, Ms., Summer 2009).
Over the weekend, a series of protests at Democratic events meant to promote health reform "organized by loose-knit coalition of conservative voters and advocacy groups, were a raucous start to what is expected to be weeks of political and ideological clashes over the health care overhaul," the New York Times reports. "Republicans said that the protests were just the beginning of spontaneous opposition to the health care proposals and that they would only gain momentum as Americans learn more about the legislation." But Democrats said they were only an effort to block discourse, and were anything but a grass-roots campaign. "This is a very coordinated effort," said one Democratic Congressman who was confronted by protestors at a grocery store (Herszenhorn and Stolberg, 8/3).
In an essay in The Washington Post, an infectious disease specialist writes that "the unspoken truth among doctors is that we objectively or subjectively ration care, and often don"t tell patients or their families." Organs, for example, "are a precious commodity, their donation strictly regulated by national guidelines. ņ¦ Because donors are scarce, it seems appropriate to ration their organs on the basis of need and other ethical and medical considerations." Medical care is also rationed through long wait times to see physicians (ranging from 11 to 50 days in major cities, according to a 2009 survey by Merritt Hawkins & Associates) or shortages of beds in a hospital.
Congressional Quarterly examines a "three-page concept paper" issued by the House Foreign Affairs Committee that lays out a plan to overhaul U.S. foreign aid. The committee suggests "giving the administration greater flexibility to control aid in exchange for greater public oversight and a performance- and need-driven allocation system," the news service writes. "The plan would reorganize aid programs around seven purposes, including "reducing poverty and alleviating human suffering," "supporting human rights and democracy," and "expanding prosperity through trade and investment,"" according to CQ. The House committee wants to enhance USAID"s role, "giving the agency a seat on the National Security Council and putting it in charge of the U.S. global AIDS plan and the Millennium Challenge Corporation," the news service writes.
Children have certainly mastered the art of selecting, negotiating and even refusing the chores their parents assign to them. This growth in personal autonomy at home over the last few decades could be the result of shrinking opportunities to participate in activities outside the home, without Mom and Dad looking over their shoulder, according to Dr. Markella Rutherford from Wellesley College in the US. Her analysis1 of back issues of the popular US magazine, Parents, maps how the portrayal of parental authority and children"s autonomy has changed over the last century. Her findings are published online in Springer"s journal Qualitative Sociology.
Professor Declan Murphy and colleagues Dr Michael Craig and Dr Marco Catani from the Institute of Psychiatry at King"s College London have found differences in the brain which may provide a biological explanation for psychopathy. The results of their study are outlined in the paper "Altered connections on the road to psychopathy", published in Molecular Psychiatry.
Three cases of patients suffering from the adverse affects of steroid-enriched dietary supplements have been reported by researchers at Henry Ford Hospital.
In its fight against an intruding virus, an enzyme in our immune system may sense certain types of viral RNA pairs, according to scientists.
When planning for surgery, patients too often don"t consider the kind of anesthesia they will receive. In fact, the choice of anesthesia can improve recovery, even outcomes.
Rheumatoid Arthritis (RA) is a chronic autoimmune disease that causes inflammation of the joints and surrounding tissues. More than 1.3 million adults in the U.S. suffer from RA with 75% of those afflicted being women. Patients with RA experience pain, stiffness, swelling, and deterioration of joints. Severe chronic pain accompanied by progressive joint destruction, disability, and disfigurement is known to increase the risk of experiencing emotional disturbances, with RA patients twice as likely to be depressed as people in the general population. Emotional wellness for persons with RA plays a critical role in disease course and disability.
Over 100 certified breastfeeding peer counselors, lactation consultants, nurses, physicians, dietitians and community health workers are expected to gather at Rush University Medical Center on Thursday, August 6 from 8 a.m. until 1 p.m. in Room 500 at 1725 W. Harrison Street, Chicago, to attend the Griffin Inaugural Conference on Breastfeeding: The Primary Foundation for Health.
Statistics released yesterday by the NHS Information Centre reflect a year when dentists were working hard to make the new dental contract of 2006 work, according to the British Dental Association (BDA). The Dental Earnings and Expenses, England and Wales, 2007/08 report, which considers the earnings of dentists who undertook NHS work in England or Wales in the second year of the new contract, paints a picture of earnings settling after a transitional year in 2006/07.
The fight against obesity has stepped up a gear with the
In a finding that challenges the increasingly popular belief that smoking marijuana is less harmful to health than smoking tobacco, researchers in Canada are reporting that smoking marijuana, like smoking tobacco, has toxic effects on cells. Their study is scheduled for the Aug. 17 issue of ACS" Chemical Research in Toxicology, a monthly journal.
Growing scientific evidence indicates that people who adhere to a special calorie-restricted diet can improve their health and could potentially add years to their lifespan, according to an article in the current issue of Chemical & Engineering News, ACS" weekly newsmagazine.
Due to workforce shortages, doctors are struggling to maintain their involvement in teaching and in research activities, according to an article published in the Medical Journal of Australia. Further, the demands for doctors to teach medical students and doctors-in-training are increasing, with even more medical students now enrolled.
The number of Americans under care for depression and other mental illnesses nearly doubled between 1996 and 2006, and the overall cost of treating them jumped by nearly two-thirds, according to the latest News and Numbers from HHS" Agency for Healthcare Research and Quality.
A study just published on bmj.com reports that the risk of heart attack is multiplied by two for men who have angina. Also their risk of suffering a heart disease-related death is three times higher than for women with the same condition.
As the U.S. prepares for a resurgence of H1N1 influenza this fall, much can be learned from looking at a previous pandemic that had similar patterns. In an article published today in Biosecurity and Bioterrorism, researchers at the Center for Biosecurity of the University of Pittsburgh Medical Center (UPMC) examined historical documents, published material, and newspaper coverage related to the 1957-58 influenza pandemic to compare the progress and severity of that outbreak with the current one. The simple, practical actions taken in 1957 allowed the country to continue functioning with minimal disruption.
As we all know from experience, people eat not only because they are hungry, but also because the food just simply tastes too good to pass up. Now, a new study in the August 6th Cell Metabolism, a Cell Press publication, helps to explain how leptin, a hormone produced by fat tissue, influences that motivation to eat.
Scientists at UC Santa Barbara have isolated a unique protein that appears to have a dual function and could lead to a "boon in medicine." The findings are published in the August issue of the Journal of Cell Biology.
Worldwide collaborative ties among researchers investigating the debilitating neurological condition multiple sclerosis (MS) have been strengthened thanks to the introduction of the first UK and Australian Fellowship Exchange programme.
During a presentation about the Health Agenda for the Americas at the "Seventh
The WHO on Tuesday maintained that roughly two billion people could become infected with the H1N1 (swine flu) virus, Reuters reports. "By the end of a pandemic, anywhere between 15-45 percent of a population will have been infected by the new pandemic virus," WHO spokeswoman Aphaluck Bhatiasevi said, adding that 30 percent, or 2 billion people worldwide, is the mid point of that estimate. "But the estimate comes with a big health warning: no one knows how many people so far have caught the new strain ... and the final number will never be known as many cases are so mild they may go unnoticed," the news service writes (Lynn, 8/4).
BSD Medical Corporation (NASDAQ:BSDM) announced that the U.S. Food and Drug Administration (FDA) has granted Humanitarian Use Device (HUD) designation for the company"s BSD-2000 Hyperthermia System for use in conjunction with radiation therapy for the treatment of cervical carcinoma patients who are ineligible for chemotherapy. This is the first of the two steps required to obtain Humanitarian Device Exemption (HDE) marketing approval, which requires BSD Medical to demonstrate the device"s safety and probable benefit in treating a disease or condition that affects fewer than 4,000 individuals in the United States per year. Now that FDA has granted the Humanitarian Use Designation for the BSD-2000, which confirms that the intended use population is fewer than 4,000 patients per year, BSD can file an HDE submission with the FDA. FDA has 75 days from the date of receipt of the HDE submission to grant or deny an HDE application. This period includes a 30-day filing period during which FDA determines whether the HDE application is sufficiently complete to permit substantive review. During this review, FDA may refine the indications for use which received HUD designation to finalize the indications for use for which HDE approval will be granted. This decision will be based on the data that are available to support the device"s HDE application. The company believes that the data previously submitted to FDA and reviewed by the agency in the company"s pending PMA application can be used to support the HDE approval, and that this previous review may expedite marketing approval for the BSD-2000.
People living with HIV will benefit from a new test developed by Victoria, Australia scientists that offers a simpler and cheaper way of monitoring the disease in sufferers, Victorian Innovation Minister Gavin Jennings said today.