Health Insurance
Researchers at the Liverpool School of Tropical Medicine (LSTM) and the University of Liverpool will work with universities across Africa as part of a ÷£30 million initiative to strengthen research into science and health on the continent.
Several statistical and biological issues need to be addressed in order to improve biomarker identification for early detection of cancer, according to a commentary published online July 2 in the Journal of the National Cancer Institute.
It"s estimated two out of three Americans are now overweight or obese*
US researchers said that undiagnosed cases of celiac disease, where the immune system has a strong adverse reaction to the protein found in
Memory loss is love"s great thief. Those who suffer aren"t just the ones who can"t remember - family, friends and loved ones agonize over how to react when the disorder begins its often inexorable progress.
Southampton"s university hospitals are to take part in clinical trials of a vaccine that could protect against numerous types of flu - including pandemics such as bird and swine flu.
The Ohio Department of Health (ODH) announced that a Butler County male in his 40s, who was infected with H1N1 influenza, died June 29. This is the first Ohio death linked to the pandemic strain of influenza. The patient had underlying health problems that may have contributed to his death.
Indiana state health officials warn Hoosiers that elevated lead levels have been found in products sold at Target stores.
Government"s announcement that the UK is moving to a new phase in the response to the current pandemic flu virus means there will be a change to the surveillance information that the Health Protection Agency will be able to provide to the media in future.
ThromboGenics NV (Euronext Brussels: THR) and co-development partner BioInvent International (OMXS: BINV) announce that they have started recruitment of a second cohort of patients for their Phase II trial of TB-402. This follows completion of recruitment of the first cohort of 100 patients ahead of schedule. TB-402 is a novel, long acting anticoagulant that is being developed for the prevention of deep vein thrombosis (DVT) following orthopaedic surgery. The decision to move ahead with the second cohort of this trial follows unanimous advice from the external efficacy and safety monitoring board to proceed using a higher dose of TB-402.
Video from portable cameras is analysed to calculate the distance of obstacles and predict the movements of people and cars. This information is then transformed and relayed to a blind person as a three-dimensional "picture" of sound.
Resuming sexual activity is expressed by patients as extremely important after a myocar÷dial infarction (MI). In spite of this, sex counselling is an area of nursing practice that is frequently neglected and needs more evidence-based knowledge.
Biogen Idec (NASDAQ: BIIB) announced data results from the CHAMPIONS (Controlled High-Risk AVONEX® (interferon beta-1a) Multiple Sclerosis (MS) Prevention Study In Ongoing Neurologic Surveillance) study, an open label follow-up to CHAMPS (Controlled High Risk Subjects AVONEX MS Prevention Study). Based on the CHAMPS study, AVONEX was granted approval for use in patients who experienced their first clinical MS episode with MRI findings. The CHAMPIONS ten-year follow up showed that patients treated immediately after their first episode had significantly less chance of experiencing a second attack versus those patients with delayed treatment. These results at ten years also indicate that 80 percent of patients taking AVONEX were below an expanded disability status scale (EDSS) score of three. These data were presented as a poster at the Annual American Academy of Neurology (AAN) meeting.
Bristol-Myers Squibb Company (NYSE: BMY) and AstraZeneca (NYSE: AZN) announced that their marketing authorization application for ONGLYZA™ (saxagliptin) received a positive opinion from the Committee for Medicinal Products for Human Use (CHMP) for the treatment of type 2 diabetes in adults as add-on therapy with metformin, a thiazolidinedione or a sulphonylurea.
Genentech, Inc. announced today that the Phase III study BRAVO showed Lucentis® (ranibizumab injection) improved vision, as measured by the primary endpoint of mean change from baseline in best-corrected visual acuity at six months, in patients with macular edema due to branch retinal vein occlusion. The safety profile of Lucentis was consistent with previous experience and no new adverse events related to Lucentis were observed in the study. Retinal vein occlusion (RVO) is a common cause of vision loss that occurs when blood flow through a retinal vein becomes blocked, such as by a blood clot.
Psychotherapy consists of a series of techniques for treating mental health, emotional and some psychiatric disorders. Psychotherapy helps the patient understand what helps them feel positive or anxious, as well as accepting their strong and weak points. If people can identify their feelings and ways of thinking they become better at coping with difficult situations.
Catalysts assist in chemical reactions without undergoing any alteration of their own. In the cells of living organisms, proteins perform this important function. They carry out the metabolism fundamental to all living processes. Proteins are instrumental in cellular respiration, they for instance reduce oxygen to water and oxidize food into carbon dioxide. This releases the energy that makes life possible at all.
A newly discovered mechanism controls whether muscle cells in blood vessels hasten the development of both atherosclerosis and Alzheimer"s disease, according to an article published online in the journal Nature.
New research from the US and Japan showed that giving the caffeine equivalent of five cups of coffee a day to aged mice with symptoms of
A group of international experts will meet at the Royal College of Obstetricians and Gynaecologists (RCOG) on the occasion of South Asia Day to discuss ways to achieve Millennium Development Goals 4 (reduce child mortality) and 5 (improve maternal health). This historic conference gathers together specialists in obstetrics and gynaecology, midwives, health care providers and policy makers to share experiences and discuss strategies to improve women"s health in South Asia.
In a bid to reduce levels of undiagnosed HIV in Cardiff, HIV and sexual health charity Terrence Higgins Trust (THT) is encouraging people who may have been at risk to attend a local service offering one-hour HIV testing. One in four people who have HIV in the UK are undiagnosed, and there are now more people living with the condition than ever before.
It has long been a mystery how the developing embryo designates those rare, precious cells destined to produce sperm and eggs -- enabling us to have offspring - since these primordial germ cells" existence is fleeting and hard to spot with the tools of biology. Now, using mouse embryonic stem cells, researchers in the Stem Cell Program at Children"s Hospital Boston have managed to recapitulate the creation of primordial germ cells (PGCs) in the lab, capturing the stem cells" gene activity as they differentiated to form PGCs. The findings, published in the July 5 issue of Nature, also offer a unique window on cancer.
Inovio Biomedical Corporation (NYSE Amex:INO), a leader in DNA vaccine design, development and delivery, announced today that it will make multiple presentations at the Annual Conference of DNA Vaccines in Asia 2009 being hosted by the International Society of DNA Vaccines July 9 - 10 at the Beijing International Convention Center. The conference, with the theme, "Advancing DNA Vaccine Technology," is co-chaired by David B. Weiner, Ph.D., professor of pathology, University of Pennsylvania School of Medicine, and chairman of Inovio"s scientific advisory board.
Diabetes UK is concerned that more than half a million people with diabetes in England are still not been screened for retinopathy.
To meet the growing needs of its high-volume emergency department (ED), Huntington Memorial Hospital has acquired Toshiba"s Aquilion® ONE dynamic volume CT system.
ATS Medical, Inc. (Nasdaq: ATSI), manufacturer and marketer of state-of-the-art cardiac surgery products and services, announced FDA clearance and the first implant of the ATS Simulus(R) Semi-Rigid Annuloplasty Band. The Simulus Semi-Rigid Annuloplasty Band was developed through the Company"s collaboration with Genesee BioMedical and represents the latest addition to the expanding portfolio of valve repair products.
A procedure that sends targeted energy into the heart through a catheter can be used to treat a common type of irregular heartbeat, but little is known about the treatment"s long-term benefits and the best methods and circumstances for applying it, according to a new report funded by HHS" Agency for Healthcare Research and Quality.
Beginning today, Hong Kong people and their children will have direct access to Filligent"s patented anti- microbial face mask, the BioMask(TM). The revolutionary mask, which traps and kills germs like H1N1 upon contact, was launched at Asia"s leading drugstore chain, Watsons, today. In addition, Hong Kong"s biggest travel agency, Hong Thai, will be providing the BioMask(TM), on a complimentary basis, to all air travelers through the end of August. Up until now, the CE-certified, specialist mask has only been available to medical and healthcare professionals. The launch and availability of the BioMask(TM) in consumer retailers and service providers is significant because, as CEO Melissa Mowbray-d"Arbela says, "The BioMask(TM) is the first "intelligent" face mask. You don"t have to be a health care worker or medical professional to use it correctly. Instead, the mask is very easy to put on, wear and dispose of properly. Thus, it"s one of the best forms of protection for ordinary people and their children during this year"s swine flu crisis."
Global biomedical sciences companies invested more than US$500 million in
Combining antidepressant drugs with electroconvulsive therapy (ECT) does a better job of reducing symptoms of severe depression and causes less memory loss than using ECT alone, according to a new study by researchers at Wake Forest University School of Medicine and colleagues.
A recent study published in the Canadian Medical Association Journal (CMAJ) reports that patients taking statins with associated muscle complaints may have structural muscle damage.
AAMC (Association of American Medical Colleges) President and CEO Darrell G. Kirch, M.D., issued the following statement on the final National Institutes of Health"s (NIH) Guidelines on Human Stem Research, published today:
Democrats and Republicans are saying that they will need to compromise on a government-run public plan if they are to meet the deadline of having a bill on the Senate floor by the August recess, The Associated Press reports.
The Medicare Rights Center (Medicare Rights) and Food Bank For New York City (Food Bank) have joined forces to enroll poor older New York City residents in programs to help them afford health care and healthy food. Funded by a $1 million grant from the Fan Fox and Leslie R. Samuels Foundation, the two advocacy organizations will help city seniors enroll in four under-utilized assistance programs, with a total project value to enrollees of $46 million.
"The nation"s largest insurers, hospitals and medical groups have hired more than 350 former government staff members and retired members of Congress in hopes of influencing their old bosses and colleagues, according to an analysis of lobbying disclosures and other records," the Washington Post reports. The Post"s analysis of lobbying disclosure records shows that three-quarters of major health firms have hired an insider to lobby on their behalf; half of those insiders once worked for the key senators and congressional committees that are now shaping the reform proposals.
Hydra Biosciences, Inc., a biotech company developing novel ion channel drugs, has announced that research published by Hydra Biosciences scientists and collaborators at Yale University for the first time identified the ion channel TRPA1 as playing an essential role in allergic asthma and demonstrated that Hydra"s TRPA1 antagonist HC-030031 effectively treated allergic asthma in mice. The paper, titled "A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma," will appear this week in Proceedings of the National Academy of Sciences (PNAS).
Aine Brady, T.D., Minister for Older People, officially launched the "Directory of Services for Older People in the Stoneybatter Area".
With neuroscience on the threshold of unprecedented advances in understanding and treating Alzheimer"s disease, Parkinson"s disease, autism, and a range of other disorders of the brain and nervous system, the American Chemical Society (ACS) has announced plans to launch a new journal devoted to the molecular basis of neurological disease.
Men are being warned that steroids can lead to premature baldness after a leading hair clinic reported an alarming rise in the number of patients affected by the designer drugs.
BioNews publishes a controversial editorial by Dr Gedis Grudzinskas, Director of Fertility Focus Professional Services. If the same standards were applied to ivf centres as cardiac surgery, one in five ivf centres in the uk would be closed immediately.
Despite growing evidence that cancer is becoming more prevalent amongst ethnic minority groups, news figures out today at the start of Ethnic Minority Cancer Awareness Week show that cancer awareness levels are critically low amongst this cohort.
The Genome Analysis Centre (TGAC) will further the UK"s capacity in genomics - the science of understanding the genetic makeup of organisms and the genetic differences that exist between individuals. This knowledge can then be used for developments that include the production of new antibiotics to fight "superbugs", breeding of new crops with increased tolerance of drought, and the breeding of livestock better able to resist emerging exotic disease. TGAC will underpin these advances as well as making a significant contribution to economic development.
Children who play an online game promoting healthy foods and beverages appear more likely to choose nutritious snacks than those who play a game promoting unhealthy products, according to a report in the July issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer"s patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer"s patients, with increasing progression of the disease.
An electronic system with personalized patient information shared by diabetes patients and their primary care providers improved diabetes care and clinical outcomes, found a new study in CMAJ (Canadian Medical Association Journal) .
Patients who survive an initial diagnosis of breast cancer often succumb to the disease years later when the cancer shows up in a different part of the body. Now, scientists have identified key signals that support the long term survival of breast cancer cells after they have spread to the bone marrow. The research, published by Cell Press in the July issue of the journal Cancer Cell, may lead to development of treatment strategies that decrease the likelihood of breast cancer recurrence in the bone and other organs.
Many people living with cancer are researching their illnesses online. In fact, research has shown that patients who use the Internet consider it a more useful of information as compared with other media. Further, patients" Internet use can encourage active communication with their physicians.
In response to a study published online in the BMJ, comparing the performance of two cardiovascular risk assessment tools, British Heart Foundation (BHF) Medical Director, Professor Peter Weissberg, said:
ACCESS PHARMACEUTICALS, INC. (OTC Bulletin Board: ACCP) announced new preclinical data demonstrating that thiarabine shows remarkable efficacy in the prevention and treatment of rheumatoid arthritis (RA). In a well-established animal model for RA, an exceptional restoration of joint structure was observed in the studies, which were conducted at Wayne State University School of Medicine and at Southern Research Institute.
Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, announced today that it has initiated a Phase 2 clinical trial of LX1032, the company"s oral drug candidate for managing gastrointestinal symptoms associated with carcinoid syndrome. LX1032 is designed to reduce serotonin production in patients with metastatic carcinoid tumors. Elevated levels of serotonin contribute to the gastrointestinal and possibly other symptoms experienced by these patients.
It is time for states to suspend, rather than terminate, the Medicaid benefits of inmates while they are incarcerated, say correctional health care experts from The Miriam Hospital in a commentary published online by the Journal of General Internal Medicine.
A recent study published in the Canadian Medical Association Journal (CMAJ) reports that diabetes care and clinical outcomes are improved by an electronic system with personalized patient information shared by diabetes patients and their primary care providers.
In addition to greatly improving overall health and longevity, losing weight is an effective fall prevention strategy for persons with obesity, according to a new study from the American College of Sports Medicine.
Black women diagnosed with breast cancer have a greater chance of dying from the disease than white women, according to a new study published online July 7 in the Journal of the National Cancer Institute.
Using magnetic resonance imaging (MRI), radiologists may be able to diagnose deep endometriosis and accurately locate lesions prior to surgery, according to a new study published in the online edition of Radiology.
New studies that analyse genetic differences across thousands of human genomes
During debate on the fiscal year 2010 appropriations bill for Washington, D.C., some House members on Tuesday "are expected to use the opportunity to introduce provisions that limit how the district may use locally derived funds," including funding for abortion services, a Washington Post editorial states. "These efforts are wrong, infringe on the district"s right to self-rule and should be voted down," the editorial adds.According to the editorial, "For years, the district has labored under a provision that prevents it from using local tax dollars to fund or subsidize abortion services." The editorial notes that the "Hyde Amendment already forbids state and local jurisdictions from using federal money for abortion services, but it does not restrict these entities from using local tax dollars."A House subcommittee last month approved $768 million in federal funds for D.C., but Rep. Jose Serrano (D-N.Y.) -- chair of the subcommittee -- "stripped the abortion provision from the appropriations bill," according to the editorial. It continues that this version of the bill is "now before the full House Appropriations Committee," and "[s]ome abortion foes in the House plan to reintroduce the abortion-funding restriction."The editorial states, "Federal lawmakers have the right to seek limits on how federal money is used, but not to impose those same limits on states." It concludes that D.C. "should be treated with the same respect afforded every other sovereign jurisdiction in the country" (Washington Post, 7/7).
Responding to the annual report from the Council for Healthcare Regulatory Excellence (CHRE), Dr. Peter Carter, Chief Executive & General Secretary of the Royal College of Nursing (RCN), said:
The U.S. Food and Drug Administration is taking several actions to reduce the risk of overdose in patients using pain medications such as Darvon and Darvocet that contain propoxyphene. The actions were taken because of data linking propoxyphene and fatal overdoses.
Michael R. Taylor, J.D., a nationally recognized food safety expert and research professor at George Washington University"s School of Public Health and Health Services, will return to the U.S. Food and Drug Administration to serve as senior advisor to the commissioner.
National research on income and wealth in Australia has confirmed AMA observations that there is a clear connection between unemployment and health.
Australia"s aged care workers have been "short-changed" by today"s decision by the Fair Pay Commission to put a freeze on minimum wages, the Australian Nursing Federation (ANF) said today.
Nurses play a key role in supporting general practice and giving people access to primary health care services, the Australian Practice Nurses Association (APNA) and Australian Nursing Federation (ANF) said after the release today of two reports on general practice and practice nurses in Australia.
Researchers at the Malaghan Institute of Medical Research in Wellington, New Zealand have found that abnormally proliferating human T-cells, rapidly dividing cancer cells such as primary myeloid and lymphoid leukemic blast cells undergo programmed cell death when exposed briefly to the investigational anti-tumor drug phenoxodiol.
Trinity Biotech plc (NASDAQ: TRIB), a leading developer and manufacturer of diagnostic products for the point-of-care and clinical laboratory markets, announced the FDA approval and US launch of its high throughput haemostasis analyzer, the Destiny Max.
SRS, the leader in high-performance hybrid EMR solutions, announced today that Southeastern Orthopedic Center has selected the SRS hybrid EMR for its 35 providers after abandoning its recently purchased CCHIT-certified electronic medical record (EMR) solution. Southeastern Orthopedic Center and Tattnall Hospital Company, LLC, located in Southeast Georgia, operate 15 physician offices, a hospital, ambulatory surgery center, and physical therapy and imaging services throughout the state.
Terumo Heart Inc., a wholly owned subsidiary of Terumo Corporation, announced reaching a critical milestone in the worldwide expansion of its DuraHeart(TM) Left-Ventricular Assist System (LVAS) as the 100th patient was treated by Latif Arusoglu, MD and Michiel Morshuis, MD, cardiothoracic surgeons at the Clinic for Thoracic and Cardiovascular Surgery, Heart and Diabetes Center NRW, University Hospital of the Ruhr-University of Bochum in Bad Oeynhausen, Germany.
NexMed, Inc. (Nasdaq: NEXM), a developer of products based on the NexACT® technology, announced the mutual decision with Novartis to terminate the licensing agreement for NM100060, a topically-applied treatment for onychomycosis, commonly known as nail fungus. NexMed entered into the exclusive, worldwide agreement with Novartis in September 2005, under which Novartis assumed all clinical development, regulatory, manufacturing and commercialization responsibilities for NM100060.
The latest work to "turn off the taps" in the brain and stop a chemical being released in excess amounts which can lead to Parkinson"s Disease - was presented at The British Pharmacological Society"s Summer Meeting in Edinburgh.
SMOKING CESSATION MAY PROVIDE IMMEDIATE BENEFIT TO HEART
One of nature"s most gripping feats of survival is now better understood. For the first time, scientists from the U.S. Department of Energy"s Lawrence Berkeley National Laboratory observed the chemical changes in individual cells that enable them to survive conditions that should kill them.
GTx, Inc. (Nasdaq: GTXI), announced the initiation of a Phase I multiple ascending dose clinical trial evaluating GTx-758, an oral LH inhibitor for first line treatment of advanced prostate cancer. A Phase I single ascending dose clinical trial in 96 subjects was successfully completed in June.
Dr. SleepGood, Inc. has announced the release of the SnoreSling™, a non-invasive fabric product that could help millions of sleep apnea and snoring sufferers, as well as their bed partners, finally get a good night"s rest.
A Monash University study has proven a critical link between obesity and the onset of Type 2 diabetes, a discovery which could lead to the design of a drug to prevent the disease.
Cardiva Medical, Inc. announced that it has received clearance from the U.S. Food & Drug Administration (FDA) for its latest technology, the Cardiva Catalyst III, which is considered the first drug coated vessel closure device in the market.
As leaders at the G8 summit in L"Aquila gather to discuss global
Patients across the country are voicing a growing desire for greater engagement in, and control over, their own medical care. A new study led by Beth Israel Deaconess Medical Center (BIDMC) will examine the impact of adding new layer of openness to a traditionally one-sided element of the doctor-patient relationship - the notes from patients" doctors" visits.
New research may help doctors pinpoint when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill. The findings may also point the way to interventions that could sustain the lives of IPF patients until life-saving transplants could be performed.
Procter & Gamble Pharmaceuticals (P&GP) announced the availability of Asacol HD (mesalamine) delayed-release tablets, which are indicated for the treatment of moderately active ulcerative colitis (UC), a form of inflammatory bowel disease. UC involves inflammation of the lining of the colon and rectum and is typically characterized by flares followed by periods of remission. Moderately active UC is characterized by tougher symptoms than mildly active UC. Asacol HD is proven to help treat these tougher flares of moderately active UC. Asacol HD was approved by the U.S. Food and Drug Administration (FDA) based on evaluations from the ASCEND studies [Assessing the Safety and Clinical Efficacy of a New Dose of 5-ASA (4.8 g/day 800 mg tablet)].
Wiley-Blackwell, the scientific, technical, medical and scholarly publishing business of John Wiley & Sons, Inc (NYSE: JWa), (NYSE: JWb), has announced that the inaugural issue of its new journal, LUTS (Lower Urinary Tract Symptoms), is now live online.
Eisai Corporation of North America announced that the U.S. Food and Drug Administration (FDA) has accepted for review the company"s supplemental new drug application (sNDA) for an alternative five-day dosing regimen for Dacogen(R) (decitabine for injection) to treat patients with myelodysplastic syndromes (MDS). MDS is a potentially life-threatening group of bone marrow diseases that limit the production of functional blood cells.
Fate Therapeutics, Inc. announced the presentation of data from its research on small molecule modulators of the Wnt pathway for osteo-regeneration at the 7th Annual Meeting of the International Society for Stem Cell Research (ISSCR) in Barcelona, Spain. In its findings, the Company demonstrated that selected Wnt activators induce the differentiation of mesenchymal stem cells to mature, bone-forming osteoblasts. The study highlights the potential for using small molecule Wnt activators as osteogenic agents. Because osteogenic agents stimulate positive bone growth, they may offer an improved course of action in clinical settings ranging from orthopedics to osteoporosis as compared to current medications aimed at preventing bone decay.
New research reveals around 22 million people suffered back pain in the last year - just under half of all UK adults (45 percent)[1]. More than one in four UK adults - nearly 13 million people - suffered from knee pain in the last year. Over 80 percent of the people with back or knee pain still suffer some pain after undergoing treatment recommended by a healthcare professional. Bupa is making APOS Treatment for knee and lower back pain available in the UK for the first time. The breakthrough treatment can eliminate the need for prescription pain relief for seven out of 10 people[2].
Terrence Higgins Trust (THT) is launching a new campaign to reduce levels of undiagnosed HIV by encouraging gay men, and particularly younger gay men, to start regularly attending sexual health clinics. The campaign will use a stand-alone website (http://www.betterclinics.co.uk), media adverts, posters, condom packs and pin badges to dispel some of the myths about clinics and what the testing process involves.
The American College of Obstetrics and Gynecology recently published new guidelines on electronic fetal monitoring in an attempt to increase consistency in the way physicians interpret and act on the results, the New York Times reports. Electronic fetal monitoring, which was introduced in the 1970s, is used during labor for more than 85% of the four million infants born alive in the U.S. annually, the Times reports. According to the Times, use of fetal monitors became standard obstetrical practice before it was known if the benefits outweighed the risks. The new guidelines refine the meaning of various readings from fetal monitors and could help doctors make better decisions about whether to intervene during labor.According to experts, the widespread adoption of fetal monitoring has produced both negative and positive consequences, including significant increases in caesarean deliveries and the use of forceps during vaginal deliveries. Monitoring has not been found to reduce the risk of either cerebral palsy or fetal death resulting from inadequate oxygen to the fetal brain, as it was intended to do. Furthermore, lawyers commonly use monitoring results to support malpractice cases that might have little merit, which in turn has driven rising malpractice insurance costs and prompted some obstetricians to stop delivering infants.The new guidelines divide monitor readings into three categories to help doctors interpret readings more consistently. The old guidelines had two categories -- reassuring and non-reassuring -- and it was up to the obstetrician to determine whether a non-reassuring reading required intervention. Under the new guidelines, the first category applies when tracings of the fetal heart rate are normal and no specific action is required. The second category is for indeterminate tracings that require evaluation, continuous surveillance and re-evaluation. Obstetricians treating patients in this category should consider other clinical factors that could affect the fetus and whether the patient could be safely moved to category one, according to Catherine Spong of the Eunice Kennedy Shriver National Institute of Child Health and Human Development, which produced recommendations on which the guidelines are based. The final category is for abnormal tracings that require immediate evaluation and efforts to reverse the abnormal heart rate. The Times reports that more refinements to the guidelines are expected to be released in 2010 (Brody, New York Times, 7/7).
Researchers in London have demonstrated the ability of adult stem cells from bone marrow (mesenchymal stem cells, or MSCs) to deliver a cancer-killing protein to tumors.
An improved Continuing Professional Development (CPD) recording system is being launched
"Adverse working conditions for primary care doctors, including time pressures and an unfavorable organizational culture, may lead to stress, burnout, and ultimately to lower quality patient care, a new study found," MedPage Today reports. The study, published in the July 7 issue of The Annals of Internal Medicine, found that "53.1% of primary care physicians reported time pressure during physical examinations, while 48.1% reported chaotic working environments. Only 23.7% felt that quality was strongly emphasized in their practices. ... Moreover, 48.8% described their jobs as moderately or highly stressful, while 26.5% reported burnout, and 30.1% said they were at least moderately likely to leave their practices within two years." The authors wrote that the findings "are disturbing at a time when recruitment and retention in primary care are of major concern."
The Elephant In The Room On Health Care Minneapolis Star Tribune
"[E]xplicit indicators to measure progress in reducing heart diseases, stroke, diabetes, cancers and chronic respiratory diseases" are missing from the U.N. Economic and Social Council (ECOSOC) agenda as it meets in Geneva this week "to focus on implementing the internationally agreed goals and commitments in regard to public health," and the "omission needs to be urgently addressed if the intent is to have a major impact on reducing poverty by 2015," Ala Alwan, WHO"s assistant director-general for Noncommunicable Diseases and Mental Health; George Alleyne, PAHO"s director emeritus; and Martin Silink, president of the International Diabetes Federation write in an opinion piece in the Hindu.
Researchers have identified a genetic signature that can predict an improved clinical outcome in patients with breast cancer, and which could help in the development of new targeted therapies.
KPBS examines the reasons why the San Diego Board of Supervisors will not support the city"s needle exchange program, which twice weekly provides clean needles to injection drug users as part of an effort to curb the spread of HIV, Hepatitis C and other blood-borne diseases. Dianne Jacob, chair of the board, said, "I think it particularly sends a wrong message to our kids. It sends a message to our kids that as county government, if we gave out clean needles for illegal drug use, that we condone illegal drug use. And we don"t. And it"s wrong." She said government support should go toward drug use prevention and treatment. Steffanie Strathdee, head of the division of global public health at the University of California-San Diego School of Medicine, has examined several needle exchange programs across the world, and said, "It hasn"t been associated with more people starting drug use at earlier ages, etc., ò€¦ In fact, it"s consistently been associated with reductions in high-risk behavior. And so there"s really no reason not to support it on a broader scale" (Goldberg, 7/8). This series of articles was supported by a Kaiser Family Foundation mini reporting fellowship.
How does Hollywood impact radiation perception? Can we treat cancer with microscopic particles acting like a Trojan horse? How does the radiation exposure our astronauts receive during space travel compare to their routine diagnostic radiology exams?
The world-wide explosion of overweight people has been called an epidemic. The inflammatory nature of obesity is widely recognized. Could it really be an epidemic involving an infectious agent? In this climate of concern over the increasing prevalence of overweight conditions in our society, investigators have focused on the possible role of oral bacteria as a potential direct contributor to obesity.
Using a combination of sensory, genetic, and in vitro approaches, researchers from the Monell Center confirm that the T1R1-T1R3 taste receptor plays a role in human umami (amino acid) taste.
Boston Medical Center (BMC) researchers have identified potential safety risks among methadone maintenance treatment (MMT) patients due to the quantity and accuracy of medical record documentation. Improved communication and coordination among substance use treatment and medical providers could mitigate and manage the potential adverse effects of methadone and interacting medications. The BMC study appears in the July issue of Journal of General Internal Medicine.
Bisphenol A, a chemical widely used in plastics and known to cause reproductive problems in the offspring of pregnant mice exposed to it, also has been found to retard the growth of follicles of adult mice and hinder their production of steroid hormones, researchers report.
With appointment waiting periods stretching as long as three-months to see a psychiatrist, Delaware County patients often don"t know where to turn for "best in class" mental health services. This barrier to care is further compounded by the fact that 67 percent of primary care physicians nationwide have trouble accessing mental health services on behalf of their patients.
Treatment with the angiogenesis inhibitor bevacizumab improved hearing and alleviated other symptoms in patients with neurofibromatosis type 2 (NF2). In a paper to appear in the July 23 New England Journal of Medicine, which is receiving early online release, researchers from Massachusetts General Hospital (MGH) report that bevacizumab treatment successfully shrank characteristic tumors in a small group of NF2 patients, the first reported successful NF2 treatment not involving surgery or radiation.
White House officials said today that getting ready for the flu in the fall, whether it is seasonal flu or the ongoing H1N1 swine flu outbreak, is a
The National Cancer Institute (NCI) has licensed the University of Utah"s Huntsman Cancer Institute (HCI) and Department of Biomedical Informatics as a cancer Biomedical Informatics Grid (caBIG®) Support Service Provider in the category of Training Materials and Services. The distinction is the first to be awarded to an academic medical institution.
MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced that it has received a notice of termination of the license agreement with AstraZeneca related to the company"s Unit Dose Budesonide (UDB) product candidate. The termination was received on July 8, 2009, effective immediately. All rights licensed to AstraZeneca in the agreement now revert to the company. MAP Pharmaceuticals plans to suspend development of UDB, which did not meet primary endpoints in a Phase 3 trial in children 12-months to eight years of age with mild asthma.
Like clothing and hairstyles, oral piercings give teens and adults a way to express themselves. While trendy, this fashion statement poses a number of potential oral and overall health care risks. It"s also important to note that oral piercings most commonly involve the tongue, and also the lips, cheeks, uvula or a combination of sites. Oral piercings have been implicated in a number of adverse oral and systemic conditions.
A potential vaccine for Alzheimer"s disease also has been shown in mice to slow the weakening of muscles associated with inclusion body myositis, a disorder that affects the elderly.
The California Immunization Coalition recently bestowed the Natalie J. Smith, MD, MPH Immunization Champion Award upon Steve Baranov, vice president for community health at the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center (LA BioMed) and executive director of South Los Angeles Health Projects.
Schering-Plough Corporation (NYSE: SGP) announced that Schering-Plough K.K., the company"s country operation in Japan, has received marketing approval for REMERON(R) /Reflex(R) (mirtazapine)15 mg Tablets for the treatment of major depressive disorder.(1) The product was developed jointly with Meiji Seika Kabushiki Kaisha, Ltd. Schering-Plough and Meiji Seika will market the product under the trade names, REMERON(R) and Reflex(R), respectively. REMERON is currently available in more than 90 countries worldwide.
Hereditary angioedema (HAE) is an autosomal dominant disease affecting approximately 10,000 people in the United States. HAE causes recurrent attacks of intense localized edema involving the skin, airway, and visceral organs. While chronic therapy with attenuated androgens or plasmin inhibitors has been the mainstay of HAE therapy, many new therapies for prophylaxis and acute treatment are on the horizon. It is important for physicians to understand the signs and symptoms of patients who present with HAE and to be familiar with the conventional and emerging therapies available to treat them.
Echo Therapeutics, Inc. (OTC Bulletin Board: ECTE), a diabetes management company developing the needle-free Symphony(TM) tCGM System as a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) system, announced that Patrick T. Mooney, M.D., Chairman and Chief Executive Officer, will present at the "Innovations in Diabetes" Conference on, Tuesday, July 14, 2009 at 5:30 pm ET. The presentation will occur live and will be held at The Pier V Hotel at the Inner Harbor in Baltimore.
The "outstanding" work of Julia Hippisley-Cox, Professor of Clinical Epidemiology and General Practice at The University of Nottingham, has been recognised by the Royal College of General Practitioners.
In recent news reports, there was a statement made that abuse experienced as a child can later lead to the development of autoimmune diseases, including lupus. There is no scientific evidence to support this statement, either in humans or animal models of lupus. Stress is sometimes listed as a "trigger" for a lupus flare in a patient that has lupus. Even this hypothesis is only supported by anecdotal data and not a well defined clinical study. There is clearly a connection between the immune system and the nervous system. Stress can induce a number of physiologic changes that can last for varying periods of time. To suggest, however, that child abuse is an accepted cause of lupus is inaccurate and unsupportable until there is clear data linking childhood abuse with later development of lupus.
"In the face of mounting Republican opposition to its healthcare agenda, the Obama administration received a boost Wednesday, winning a preliminary agreement with leading hospital groups to cut federal payments to the industry over the next decade," The Los Angeles Times reports. "Under the plan, negotiated primarily by Senate Finance Committee Chairman Max Baucus (D-Mont.), hospitals would accept $155 billion in cuts if the administration and its congressional allies succeeded in extending health insurance to tens of millions of people who are now without coverage. None of the hospital groups has signed a written agreement backing the cuts, nor is there any guarantee that the cuts will be included in versions of the healthcare legislation being developed by lawmakers other than Baucus" (Levey, 7/9).
As more specific legislative language emerges on health care, "small business organizations are encouraging members to make their views known through e-mails, letters, phone calls and personal visits" to members of Congress, but "the message is a decidedly mixed one," Kaiser Health News reports. "Small business, a powerful constituency in every congressional district, no longer speaks with one voice on health care. Many of the bigger and more powerful groups that represent small businesses, including the National Federation of Independent Business (NFIB) and the U.S. Chamber of Commerce, have long been allied with Republicans and are lobbying hard against the public option and the employer mandate." But newer, less conservative groups, including the Main Street Alliance, are advocating for those same hot button issues.
Sweeping healthcare legislation in Congress includes money for walking paths, streetlights, jungle gyms, and even farmers" markets. While supporters cite their importance for preventative health, critics see the billions of dollars for such provisions in the Senate and House versions as pure pork.
"Long second shrift to other medical training, nursing education has taken on new relevance as the country faces a drastic shortage of nurses and a thin job market overall," The Dallas Morning News reports.
IRIN reports that Ghanaians "are mixing high hopes with caution" in anticipation of President Obama"s arrival in the country Friday - "his first visit to sub-Saharan Africa." Obama is expected to "make a major policy statement," according to IRIN. The article looks back at some of the commitments that former Presidents Bush and Clinton previously made to Africa (7/8).
Giovanni Parmigiani, PhD, a noted leader in applying bioinformatics tools to cancer studies and medical decision-making, has been appointed professor of biostatistics at Harvard School of Public Health (HSPH) and as chair of the Department of Biostatistics and Computational Biology at Dana-Farber Cancer Institute.
Changing Humanitarian Messaging Could Save More People
OGX-011 survival benefit: an even better Hazard Ratio.
WHO Launches International Network To Take On Noncommunicable Disease
President Obama has announced that two Fred Hutchinson Cancer Research Center investigators have been awarded the nation"s highest honor for scientists at the beginning of their independent research careers. Basic scientist Harmit Singh Malik, Ph.D., and cancer-prevention researcher Ulrike "Riki" Peters, Ph.D., are among 100 researchers to receive the prestigious 2008 Presidential Early Career Award for Scientists and Engineers (PECASE). Each will be honored in a ceremony this fall at the White House.
In research that could lead to new asthma drugs, scientists at Yale School of Medicine, Hydra Biosciences of Cambridge, Massachusetts, and the University of California, San Francisco have discovered that a protein may be a trigger of allergy-induced asthma in mice. They also demonstrated how a drug known to reduce inflammatory and neuropathic pain may also inhibit asthma symptoms in mice. Their paper is published in the May 18-22 online Early Edition of the Proceedings of the National Academy of Sciences.
Researchers from Case Western Reserve University School of Medicine identified a novel link between ITCH, a gene known to regulate inflammation in the body and NOD2, a gene which causes the majority of genetic Crohn"s Disease diagnoses. ITCH, when malfunctioning, causes widespread inflammatory diseases, including inflammatory bowel disease, gastritis, uncontrolled skin inflammation, and pulmonary pneumonitis. Derek Abbott, M.D., Ph.D., and his team of researchers found that ITCH also influences NOD2-induced inflammation. These findings, published in the August 11th issue of Current Biology, suggest a common pathophysiology exists between multiple inflammatory diseases. The unexpected finding of the interaction between these genes offers the possibility of a new drug target, which would be effective in treating Crohn"s disease - a chronic disorder causing inflammation of the gastrointestinal tract.
The strain of influenza, A/H1N1, that is currently pandemic in humans has been shown to be infectious to pigs and to spread rapidly in a trial pig population.
Aperio Technologies, Inc., (Aperio), a global leader in digital pathology for the healthcare and life sciences industry, is pleased to announce the launch of a digital pathology solution for Immunohistochemistry (IHC) designed specifically for the clinical market. Aperio"s digital IHC solution is the only commercially available FDA-cleared system allowing pathologists to run quantitative IHC image analysis while reading slides on a computer monitor.
Surgeons from Hospital for Special Surgery in New York have identified a drilling technique that improves the outcome of surgery to reconstruct the anterior cruciate ligament (ACL). The news is being presented during the annual meeting of the American Orthopedic Society for Sports Medicine, June 9 -12, in Keystone. Colo.
Osmetech plc (LSE:OMH), the fast growing international molecular diagnostics company announces that it has received US Food & Drug Administration ("FDA") 510(k) clearance for its eSensor® Cystic Fibrosis Genotyping Test for use on the eSensor® XT-8 System. This multiplex test is used for cystic fibrosis carrier screening for adults of reproductive age, as an aid in newborn screening for cystic fibrosis, and as a confirmatory diagnostic test for cystic fibrosis in newborns and children.
Revance Therapeutics, Inc. ("Revance") announces that RT001, a topical botulinum toxin type A, under investigation for the treatment of crow"s feet wrinkles, demonstrated efficacy and safety in a US Phase 2b clinical study. The randomized, double-blind, parallel-group, dose-finding study showed efficacy versus placebo at primary and multiple secondary endpoints.
Although the fact that we generate new brain cells throughout life is no longer disputed, their purpose has been the topic of much debate. Now, an international collaboration of researchers made a big leap forward in understanding what all these newborn neurons might actually do. Their study, published in the July 10, 2009, issue of the journal Science, illustrates how these young cells improve our ability to navigate our environment.
A psychologist who investigated the effects of childbearing on women"s body image will present her findings at the British Psychological Society"s Division of Counselling Psychology annual conference, held at the University of Warwick.
22nd Congress of the European College of Neuropsychopharmacology (ECNP), 12 - 16 September 2009, Istanbul, Turkey
New York state"s decision last month to allow state-funded embryonic stem cell researchers to pay women for donating their eggs had drawn support from many scientists and doctors but fueled debate among some ethicists, Long Island Newsday reports. The state"s Empire State Stem Cell Board said that researchers can pay women up to $10,000 as compensation for their time and the invasive nature of the procedure.Scientists and research advocates say the decision could boost important research into cures of serious diseases while attracting investments and new jobs to the state. Opponents raise ethical concerns about using taxpayer money for research that some people find morally objectionable. Some also contend that payment might exploit low-income women, according to Newsday. The National Academy of Sciences and NIH do not permit payments to research participants beyond reimbursement.Thomas Berg -- director of the Westchester Institute for Ethics and the Human Person and a Roman Catholic priest opposed to embryonic stem cell research -- cast the sole dissenting vote in the stem cell board"s decision. Berg said the board ignored his suggestions to open the discussion to the public. However, Samuel Packer -- a member of the board and chair emeritus at the North Shore-Long Island Jewish Health System"s Department of Ophthalmology -- said the decision was made during a public meeting following a "long, lively debate." Packer said, "At some point the dissenting voice can"t stop the progress of science or anything else in society." He added, "There is a direct link between having better eggs and doing better research" (Ochs, Long Island Newsday, 7/9).
President Obama during his speech at Notre Dame, "fought back" antiabortion-rights protesters "not with harsh words but with the most devastating weapons in his political arsenal: a call for "open hearts," "open minds," "fair-minded words" and a search for "common ground,"" Washington Post columnist E.J. Dionne writes. Dionne continues that as "Obama"s opponents seek to reignite the culture wars," the president has "refused to join" and instead "opted for humility." Dionne writes that Obama "did all this without skirting the abortion question and without flinching from the "controversy surrounding my visit here."" In what might have been Obama"s "most radical and the most conservative speech of his presidency," he "[a]cknowledg[ed] the Roman Catholic Church"s role in supporting his early community organizing work," while drawing "on the res of Catholic social thought" that "combines opposition to abortion with a sharp critique of economic injustice and thus doesn"t squeeze into the round holes of contemporary ideology," according to Dionne.In his speech, Obama "tried to undo mistakes made early in his administration, making clearer, for example, that his revisions of an earlier Bush executive order on the rights of health professionals would continue to "honor the conscience of those who disagree with abortion,"" Dionne continues. In addition, Obama "paid more respect to opponents of stem cell research -- he spoke of their "admirable conviction about the sacredness of life" -- than he had in his original announcement altering Bush"s policies," Dionne writes. He adds that on the issue of abortion rights, "Obama endorsed a broad agenda: "Let"s reduce unintended pregnancies. Let"s make adoption more available. Let"s provide care and support for women who do carry their children to term.""However, it "was hard to square that message with the rage directed toward Obama" and Notre Dame"s president, the Rev. John Jenkins, by their opponents, Dionne says. "By facing their arguments head-on and by demonstrating his attentiveness to Catholic concerns, Obama strengthened moderate and liberal forces inside the church itself," according to Dionne. He concludes, "He also struck a forceful blow against those who would keep the nation mired in culture-war politics without end. Obama"s opponents on the Catholic right placed a large bet on his Notre Dame visit. And they lost" (Dionne, Washington Post, 5/18).
CNN reports on Alfonso Torress-Cook and his efforts to eliminate fatal infections at Pacific Hospital of Long Beach, California: "Torress-Cook is part of a growing movement in medicine that no longer accepts hospital-acquired infections as inevitable complications. Every year, such infections sicken 1.7 million and kill 99,000 people in the United States."
"The Senate dealt a blow to the drug lobby Thursday by voting to permit people in the United States to order lower-cost drugs from Canada over the Internet," the Associated Press/Arizona Republic reports. The drugs in question are often made in the U.S., and then sold abroad for lower prices than at home because because of government policies in many other countries. The bill would make it legal to re-import those drugs more readily. The drug provision passed as an amendment to a Department of Homeland Security funding bill and was introduced by Republican Louisianna Sen. David Vitter (Taylor, 7/9).
"As the recession has cost more people their jobs and their health insurance, local hospitals have seen more patients show up with no way to pay," reports KUOW, a Washington State public radio station. "Hospitals in Washington are required to provide free care to anyone living below the poverty line, if they ask for it. But some hospitals give more freely than others."
Twenty-six people representing a coalition of five HIV/AIDS groups from Washington, D.C., Philadelphia and New York were arrested on Thursday for unlawfully demonstrating in the Capitol rotunda, the AP/Washington Post reports (7/9). According to Politico, the protestors were demanding "congressional action on three AIDS priorities: the end of the federal ban on syringe exchange, increased housing funding for [people living with AIDS] and significant increases in U.S. international AIDS contributions" (McGrane, 7/9). The group contends that the Obama "administration"s budget proposal "essentially flatlines global AIDS funding,"" CNN.com reports. In a statement, Omolola Adele-Oso of DC Fights Back, said, "HIV is not in recession. So why are we bailing out the bankers with $9 trillion, but breaking promises to fund life-saving AIDS programs in the U.S. and around the world at a fraction of that cost?" (7/9).
The secret to longevity may lie in an enzyme with the ability to promote a robust immune system into old age by maintaining the function of the thymus throughout life, according to researchers studying an "anti-aging" mouse model that lives longer than a typical mouse.
Researchers from Boston University School of Medicine (BUSM) and collaborators have discovered and analyzed several new compounds, collectively called the ""EUK-400 series,"" which could someday be used to prevent radiation-induced injuries to kidneys, lungs, skin, intestinal tract and brains of radiological terrorism victims. The findings, which appear in the June issue of the Journal of Biological Inorganic Chemistry, describe new agents which can be given orally in pill form, which would more expedient in an emergency situation.
Infections of wounds, pneumonia, etc. in hospitals in particular are often caused by bacteria called Pseudomonas aeruginosa. Once they reach a certain density, colonies of Pseudomonas aeruginosa produce virulence factors and can enter into a slimy state, a biofilm, which prevents antibiotics from penetrating. The process of quorum sensing, which cells use to "sense" cell density, is triggered when the concentration of certain signaling compounds generated by the bacteria reaches a threshold level. A team working with Rustem F. Ismagilov at the University of Chicago has now demonstrated that the absolute number of cells is irrelevant; only the number of bacteria in a given volume plays a role. As the researchers report in the journal Angewandte Chemie, they were even able to trigger quorum-sensing processes in single cells when these were confined in extremely small volumes.
Oral healthcare could hold the key to beating obesity according to new dental research*.
The number of suicides in England are at an all-time low, Care Services Minister Phil Hope announced as he published the latest annual report on suicide prevention.
Sequel Systems, Inc. announced it supports the recommendations from the US. Department of Health and Human Services" Meaningful Use Workgroup for the definition of "meaningful use" as it pertains to electronic health records (EHR).